Pre_GI Gene

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Host: NC_008767 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_008767:927810 Neisseria meningitidis FAM18, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from a patient with meningococcal septicemia. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.


StartEndLengthCDS descriptionQuickGO ontologyBLASTP
927810928058249hypothetical proteinBLASTP
9281709294531284putative citrate synthaseQuickGO ontologyBLASTP
9296589324862829putative 2-oxoglutarate dehydrogenase E1 componentQuickGO ontologyBLASTP
9325869338271242putative dihydrolipoamide succinyltransferase E2 componentQuickGO ontologyBLASTP
9341929356251434putative dihydrolipoamide dehydrogenase E3 componentQuickGO ontologyBLASTP
935750936037288hypothetical protein
9361379373031167putative succinyl-CoA synthetase beta subunitQuickGO ontologyBLASTP
937314938204891putative succinyl-CoA synthetase alpha subunitQuickGO ontologyBLASTP
938439938768330hypothetical proteinBLASTP
939090939734645BLASTP
9397489418022055putative ATP-dependent helicaseQuickGO ontologyBLASTP
9418179446632847putative excinuclease ABC subunit AQuickGO ontologyBLASTP
944818945615798hypothetical proteinBLASTP
9472789495722295putative outer-membrane receptor proteinQuickGO ontologyBLASTP
949976950566591putative anthranilate synthase component IIQuickGO ontologyBLASTP