Pre_GI Gene

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Host: NC_008767 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_008767:804655 Neisseria meningitidis FAM18, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from a patient with meningococcal septicemia. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
804655805221567hypothetical proteinBLASTP
805287805703417putative periplasmic proteinQuickGO ontologyBLASTP
805765806664900RdgC proteinQuickGO ontologyBLASTP
8066958081521458putative GTP-binding proteinQuickGO ontologyBLASTP
808302808931630hypothetical proteinBLASTP
8089328102271296putative histidyl-tRNA synthetaseQuickGO ontologyBLASTP
810354811019666putative periplasmic proteinQuickGO ontologyBLASTP
811292811828537hypothetical proteinBLASTP
811996812196201hypothetical proteinBLASTP
812788813153366hypothetical proteinBLASTP
813135813680546hypothetical proteinBLASTP
813843814139297hypothetical proteinBLASTP
814381814671291hypothetical proteinBLASTP
814991815239249hypothetical proteinBLASTP
815285815653369hypothetical proteinBLASTP
815999816394396putative integral membrane proteinQuickGO ontologyBLASTP
816437817306870putative periplasmic proteinQuickGO ontologyBLASTP
817471818394924hypothetical proteinBLASTP
818472819113642hypothetical proteinBLASTP
819168819959792putative transferaseQuickGO ontologyBLASTP
82012582020076tRNA-ThrQuickGO ontologyBLASTP
82023582031076tRNA-ThrQuickGO ontologyBLASTP
820452821243792putative 3-methyl-2-oxobutanoate hydroxymethyltransferaseQuickGO ontologyBLASTP
821366822202837putative pantoate--beta-alanine ligaseQuickGO ontologyBLASTP
8223618242111851putative periplasmic proteinQuickGO ontologyBLASTP
824294824932639putative outer membrane lipoproteinQuickGO ontologyBLASTP
824942825787846hypothetical proteinBLASTP