Pre_GI Gene

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Host: NC_003112 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003112:603879 Neisseria meningitidis MC58, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The B serogroup is responsible for many of the meningitis outbreaks in the developed world. This strain was isolated from a case of invasive infection. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
6038796051261248glutamyl-tRNA reductaseQuickGO ontologyBLASTP
605402605974573NosR-related proteinQuickGO ontologyBLASTP
6060286070621035copper ABC transporter periplasmic copper-binding proteinQuickGO ontologyBLASTP
607120607740621copper ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
607879608373495putative protein disulfide isomerase NosLQuickGO ontologyBLASTP
6084616101221662electron transfer flavoprotein-ubiquinone oxidoreductaseQuickGO ontologyBLASTP
610252610794543putative bacteriocin resistance proteinQuickGO ontologyBLASTP
612020612688669IS1016C2 transposaseQuickGO ontologyBLASTP
613279614094816FrpC operon proteinQuickGO ontologyBLASTP
6141116180193909putative iron-regulated protein FrpAQuickGO ontologyBLASTP
618299619213915putative adhesinQuickGO ontologyBLASTP
619290620165876membrane proteinQuickGO ontologyBLASTP
620189620944756ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
62123562160036650S ribosomal protein L19QuickGO ontologyBLASTP
621616622365750tRNA guanine-N1-methyltransferaseQuickGO ontologyBLASTP
62236562287451016S rRNA-processing proteinQuickGO ontologyBLASTP
62289062313524630S ribosomal protein S16QuickGO ontologyBLASTP
6231806256062427hypothetical proteinBLASTP
6257246271301407sensor histidine kinaseQuickGO ontologyBLASTP