Pre_GI Gene

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Host: NC_008767 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_008767:84950 Neisseria meningitidis FAM18, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from a patient with meningococcal septicemia. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
84950859661017putative lipoproteinQuickGO ontologyBLASTP
8597786174198hypothetical proteinBLASTP
86600880001401putative outer membrane transport proteinQuickGO ontologyBLASTP
88308897801473pyruvate kinaseQuickGO ontologyBLASTP
9004190370330probable IS1016 transposase partial CDSQuickGO ontologyBLASTP
9133291568237hypothetical proteinBLASTP
9156291789228hypothetical proteinBLASTP
9216192349189putative inner membrane proteinQuickGO ontologyBLASTP
9235692508153hypothetical proteinBLASTP
9260992746138putative inner membrane proteinQuickGO ontologyBLASTP
92791940561266putative protein export proteinQuickGO ontologyBLASTP
94059961462088putative protein export proteinQuickGO ontologyBLASTP
96416974231008putative IS1106 transposaseQuickGO ontologyBLASTP
9760597751147hypothetical proteinBLASTP
9855699107552putative inner membrane proteinQuickGO ontologyBLASTP
99384100043660putative periplasmic peptidase bacteriocin resistanceQuickGO ontologyBLASTP
100024100260237putative inner membrane proteinQuickGO ontologyBLASTP
101184101342159putative lipoproteinQuickGO ontologyBLASTP
101339102181843hypothetical proteinBLASTP
102420103340921aspartate carbamoyltransferase catalytic chainQuickGO ontologyBLASTP
103350103808459aspartate carbamoyltransferase regulatory chainQuickGO ontologyBLASTP
103873104538666putative inner membrane proteinQuickGO ontologyBLASTP
1046011058181218putative periplasmic protein possibly peptidoglycan-bindingQuickGO ontologyBLASTP
106002106505504polypeptide deformylaseQuickGO ontologyBLASTP
106592107518927methionyl-tRNA formyltransferaseQuickGO ontologyBLASTP
1075971088561260SUN-family proteinQuickGO ontologyBLASTP
108822109421600hypothetical proteinBLASTP
1094211115382118putative two-component sensor kinaseQuickGO ontologyBLASTP
1115311128081278putative two-component trancriptional regulatorQuickGO ontologyBLASTP