Pre_GI Gene

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Host: NC_003112 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_003112:364869 Neisseria meningitidis MC58, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: The B serogroup is responsible for many of the meningitis outbreaks in the developed world. This strain was isolated from a case of invasive infection. Causes septicemia and meningitis. The second of two pathogenic Neisseria, this organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
364869365678810shikimate 5-dehydrogenaseQuickGO ontologyBLASTP
3659783673961419glutamate--ammonia ligaseQuickGO ontologyBLASTP
3675523688351284AmpG-related proteinQuickGO ontologyBLASTP
368832369107276hypothetical proteinBLASTP
36921336929381hypothetical protein
369618369755138hypothetical protein
370096370869774FrpC operon proteinQuickGO ontologyBLASTP
370886371161276iron-regulated protein FrpC truncationQuickGO ontologyBLASTP
3712483723811134hypothetical proteinBLASTP
372445372831387hypothetical proteinBLASTP
372900373358459hypothetical proteinBLASTP
373339373728390hypothetical proteinBLASTP
373860374237378hypothetical proteinBLASTP
374259374666408hypothetical proteinBLASTP
374672375349678hypothetical proteinBLASTP
375564375923360hypothetical proteinBLASTP
3759263773291404MafB-related proteinQuickGO ontologyBLASTP
377333378274942mafA proteinQuickGO ontologyBLASTP
378271378387117hypothetical protein
3783943795241131hypothetical proteinBLASTP
3798153813891575putative phosphate permeaseQuickGO ontologyBLASTP
3817423831631422coproporphyrinogen III oxidaseQuickGO ontologyBLASTP
383368384102735transcriptional regulator CrpFnr familyQuickGO ontologyBLASTP
384215385165951cys regulon transcriptional activatorQuickGO ontologyBLASTP