Pre_GI Island

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n1_4mer:GRV/n1_4mer:RV = (Global Relative Variance of OU patterns) / (Local Relative Variance of OU patterns)

n0_4mer:D = Distance between local and global OU patterns

n0_4mer:PS = Distance between 2 strands of same DNA molecule

Selected loci indicated by large D, increased GRV associated with decreased RV and moderate increase in PS

NC_002945: Mycobacterium bovis AF2122/97, complete genome

NCBI: NC_002945

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection. Causative agent of classic bovine tuberculosis. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced.

Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

#StartEndLengthIsland TextGRV_RVDPSNeighboursClusterSub ClusterBLASTNKey Word ConfirmationOther DB ConfirmationDownload Island
147683550063823804Island text1.8088718.459727.5281Neighbours11BLASTN+476835.gbk
283102985365622628Island text1.7444917.413716.9394Neighbours11BLASTN+831029.gbk
31095337*111759922263Island text1.7646818.228426.5014Neighbours11BLASTN+IslandViewer 1095337.gbk
41621765164826226498Island text1.4807719.430920.7943Neighbours11BLASTN+1621765.gbk
51680751170398323233Island text1.7811119.975425.131Neighbours11BLASTN+1680751.gbk
61856228188073824511Island text1.7342219.87235.2998Neighbours11BLASTN+1856228.gbk
72757821278170823888Island text1.4989317.078121.5982Neighbours11BLASTN2757821.gbk
83073370309459921230Island text1.5714421.397734.2086Neighbours11BLASTN+IslandViewer 3073370.gbk
93246278326609919822Island text1.539216.987331.1488Neighbours11BLASTN+IslandViewer 3246278.gbk
103429315345013820824Island text1.5700217.836818.3823Neighbours11BLASTN+IslandViewer 3429315.gbk
113735141376077425634Island text1.4717221.425129.5286Neighbours11BLASTN+IslandViewer 3735141.gbk