Pre_GI Gene

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Host: NC_002945 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_002945:3735141 Mycobacterium bovis AF2122/97, complete genome

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection. Causative agent of classic bovine tuberculosis. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
373514137384163276error-prone DNA polymeraseQuickGO ontologyBLASTP
373857237399121341hypothetical proteinBLASTP
373995437411291176trehalose 6-phosphate phosphataseQuickGO ontologyBLASTP
37413663742256891enoyl-CoA hydrataseQuickGO ontologyBLASTP
374226137436881428amidase AmiDQuickGO ontologyBLASTP
37437963744449654hypothetical proteinBLASTP
374454137459921452cyclaseQuickGO ontologyBLASTP
37459973746887891hypothetical proteinBLASTP
3746896374870118061-deoxy-D-xylulose-5-phosphate synthaseQuickGO ontologyBLASTP
37487313749720990LYTB-like protein LYTB1QuickGO ontologyBLASTP
374972037507721053polyprenyl synthetase IdsBQuickGO ontologyBLASTP
37515263751918393hypothetical proteinBLASTP
37519183752226309hypothetical proteinBLASTP
37523753753079705transposaseQuickGO ontologyBLASTP
37530693753746678transposaseQuickGO ontologyBLASTP
375393637561852250PE-PGRS family proteinQuickGO ontologyBLASTP
37562563757128873dehydrogenaseQuickGO ontologyBLASTP
37572023757912711lipoprotein LpqDQuickGO ontologyBLASTP
375795837599101953short chain dehydrogenaseQuickGO ontologyBLASTP
37599113760774864cyclopropane-fatty-acyl-phospholipid synthase 1 CMAA1 cyclopropane fatty acid synthase CFA synthase cyclopropane mycolic acid synthase 1QuickGO ontologyBLASTP