Pre_GI Gene

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Host: NC_002945 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_002945:1621765 Mycobacterium bovis AF2122/97, complete genome

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection. Causative agent of classic bovine tuberculosis. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
162176516233091545glucose-6-phosphate 1-dehydrogenaseQuickGO ontologyBLASTP
162330616244271122transaldolaseQuickGO ontologyBLASTP
162444416265462103transketolaseQuickGO ontologyBLASTP
162698516312114227PE-PGRS family proteinQuickGO ontologyBLASTP
16316131632539927protoheme IX farnesyltransferaseQuickGO ontologyBLASTP
163258816349752388PE-PGRS family proteinQuickGO ontologyBLASTP
163512716363921266transcriptional activator proteinQuickGO ontologyBLASTP
16364201637406987quinone reductaseQuickGO ontologyBLASTP
16374261638289864hypothetical proteinBLASTP
16382391639171933unidentified antibiotic-transport integral membrane ABC transporterQuickGO ontologyBLASTP
16392831640068786unidentified antibiotic-transport integral membrane ABC transporterQuickGO ontologyBLASTP
16400651641006942unidentified antibiotic-transport ATP-binding protein ABC transporterQuickGO ontologyBLASTP
164110916428841776integral membrane proteinQuickGO ontologyBLASTP
16429321643738807transcriptional regulatory proteinQuickGO ontologyBLASTP
164373516462752541hypothetical proteinBLASTP
164627216474651194hypothetical proteinBLASTP
16474621648262801ABC transporter ATP-binding proteinQuickGO ontologyBLASTP