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Query: NC_016911:278415:283471 Rickettsia rickettsii str. Hauke chromosome, complete genome

Start: 283471, End: 283578, Length: 108

Host Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens and is composed of two groups, the spotted fever group, and the typhus group. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017058:1152361:116537211653721165587216Rickettsia australis str. Cutlack chromosome, complete genomehypothetical protein3e-0857.4
NC_009879:260000:266693266693266797105Rickettsia canadensis str. McKiel, complete genomehypothetical protein3e-0753.9
NC_003103:266013:279081279081279296216Rickettsia conorii str. Malish 7, complete genomehypothetical protein4e-0857
NC_015866:274550:284761284761284976216Rickettsia heilongjiangensis 054 chromosome, complete genomehypothetical protein3e-0857.4
NC_016931:269537:276275276275276490216Rickettsia massiliae str. AZT80 chromosome, complete genomehypothetical protein2e-0650.8
NC_017043:990395:100069410006941000909216Rickettsia montanensis str. OSU 85-930 chromosome, complete genomehypothetical protein4e-0857
NC_017044:278500:283565283565283780216Rickettsia parkeri str. Portsmouth chromosome, complete genomehypothetical protein2e-0754.3
NC_016909:278327:283383283383283490108Rickettsia rickettsii str. Arizona chromosome, complete genomehypothetical protein2e-1374.3
NC_016913:859931:885480885480885587108Rickettsia rickettsii str. Brazil chromosome, complete genomehypothetical protein2e-1374.3
NC_016908:278457:283510283510283617108Rickettsia rickettsii str. Colombia chromosome, complete genomehypothetical protein2e-1374.3
NC_016914:278500:283604283604283711108Rickettsia rickettsii str. Hino chromosome, complete genomehypothetical protein2e-1374.3
NC_016915:278000:283153283153283260108Rickettsia rickettsii str. Hlp#2 chromosome, complete genomehypothetical protein2e-1374.3
NC_016639:274157:284240284240284455216Rickettsia slovaca 13-B chromosome, complete genomehypothetical protein4e-0857
NC_017065:274165:284248284248284463216Rickettsia slovaca str. D-CWPP chromosome, complete genomehypothetical protein4e-0857