Pre_GI Gene

Some Help

Host: NC_016913 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016913:859931 Rickettsia rickettsii str. Brazil chromosome, complete genome

Host Lineage: Rickettsia rickettsii; Rickettsia; Rickettsiaceae; Rickettsiales; Proteobacteria; Bacteria

General Information: This genus, like other Rickettsial organisms such as Neorickettsia and Anaplasma, are obligate intracellular pathogens and is composed of two groups, the spotted fever group, and the typhus group. The latter is composed of two organisms, Rickettsia prowazekii and Rickettsia typhi. The bacteria are transmitted via an insect, usually a tick, to a host organism, in this case humans, where they target endothelial cells and sometimes macrophages. They attach via an adhesin, rickettsial outer membrane protein A, and are internalized where they persist as cytoplasmically free organisms. This organism was first identified by Dr. Howard Rickets as the causative agent of Rocky Mountain Spotted Fever, which was originally named for its geographic distribution at the time, it is now known to be widespread throughout the North American continent. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. This bacterium is an obligate intracellular pathogen that infects primarily the vascular endothelium, and occasionally smooth muscle tissue. It is passed to the human host from a tick bite, and the tick acts as both a natural reservoir and a vector for disease transmission. Once the organism is endocytosed by the host cell, it quickly escapes the phagozome, and replicates intracellularly, causing cell death and tissue damage. The disease is characterized by a spotted rash and has a high mortality rate if left untreated.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
859931860347417hypothetical proteinBLASTP
860565860714150hypothetical proteinBLASTP
861380861544165multidrug resistance ABC transporter ATP-binding proteinpermeaseQuickGO ontologyBLASTP
861599861829231multidrug resistance ABC transporter ATP-binding proteinpermeaseQuickGO ontologyBLASTP
861904862017114hypothetical proteinBLASTP
862103862246144hypothetical proteinBLASTP
8627038646101908threonyl-tRNA synthetaseQuickGO ontologyBLASTP
8647078662931587hypothetical proteinBLASTP
866510867220711phosphoribosylaminoimidazolesuccinocarboxamide synthaseQuickGO ontologyBLASTP
8673748686121239peptidase M16 family proteinQuickGO ontologyBLASTP
868689869537849beta 14 glucosyltransferaseQuickGO ontologyBLASTP
869530869790261protein RelEQuickGO ontologyBLASTP
869801870043243protein RelBQuickGO ontologyBLASTP
8702458712641020cytochrome d ubiquinol oxidase subunit IIQuickGO ontologyBLASTP
8712728726421371cyanide-insensitive cytochrome bd-type quinol oxidase subunit IQuickGO ontologyBLASTP
872794873066273hypothetical proteinBLASTP
8732468750151770multidrug ABC transporter ATP-binding proteinQuickGO ontologyBLASTP
875083875217135hypothetical proteinBLASTP
875301875540240hypothetical proteinBLASTP
875711876139429hypothetical proteinBLASTP
8763068774031098S-adenosylmethionine--tRNA ribosyltransferase-isomeraseQuickGO ontologyBLASTP
8776188786701053ATPaseQuickGO ontologyBLASTP
878829879395567hypothetical proteinBLASTP
883177883620444hypothetical proteinBLASTP
883837884748912methionyl-tRNA formyltransferaseQuickGO ontologyBLASTP
884745885272528peptide deformylaseQuickGO ontologyBLASTP
885480885587108hypothetical proteinBLASTP
885544885696153hypothetical proteinBLASTP
885723885908186hypothetical proteinBLASTP
886030886149120hypothetical proteinBLASTP
886270886554285hypothetical proteinBLASTP
886599886889291transporterQuickGO ontologyBLASTP
886861887103243transporterQuickGO ontologyBLASTP
8879268906432718DNA gyrase subunit AQuickGO ontologyBLASTP
891074891181108hypothetical proteinBLASTP
891551891814264DNA gyrase subunit AQuickGO ontologyBLASTP
892097892654558multidrug resistance ABC transporter ATP-binding proteinpermeaseQuickGO ontologyBLASTP