Pre_GI: BLASTN Hits

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Query: NC_012658:545840 Clostridium botulinum Ba4 str. 657 chromosome, complete genome

Start: 545840, End: 567104, Length: 21265

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum Ba4 str. 657 was isolated from an infant botulism case in 1976. The strain is a bivalent Ba strain, that simultaneously produces two different toxin types. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_010516:583870*58387060159917730Clostridium botulinum B1 str. Okra, complete genome02884BLASTN svgBLASTP svg
NC_014328:34829803482980351005727078Clostridium ljungdahlii ATCC 49587 chromosome, complete genome7e-1383.8BLASTN svgBLASTP svg
NC_008261:225425*22542525641730993Clostridium perfringens ATCC 13124, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_008261:421000*42100043770016701Clostridium perfringens ATCC 13124, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_008262:227354*22735427081243459Clostridium perfringens SM101, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_003366:25548025548029721641737Clostridium perfringens str. 13, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_004557:691944*69194471563123688Clostridium tetani E88, complete genome8e-25123BLASTN svgBLASTP svg
NC_004557:25524182552418257431921902Clostridium tetani E88, complete genome2e-0661.9BLASTN svgBLASTP svg
NC_011661:961129*96112998426123133Dictyoglomus turgidum DSM 6724, complete genome2e-0661.9BLASTN svgBLASTP svg