Query: NC_011896:332939 Mycobacterium leprae Br4923, complete genome
Start: 332939, End: 354033, Length: 21095
Host Lineage: Mycobacterium leprae; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria
General Information: This strain was isolated from a human skin biopsy in Brazil, and passaged in nude mice and armadillos. The bacterium is a close relative of M. tuberculosis. However, compared to the latter, the genome of M. leprae is smaller due to reductive genome evolution, with many important metabolic activities including siderophore production, part of the oxidative chain, most of the microaerophilic and anaerobic respiratory chains, and numerous catabolic systems and their regulatory circuits eliminated due to extensive recombination events between dispersed repetitive sequences. It is evident that this species has undergone massive genome reduction over time as a result of its parasitic nature, discarding more than half its genes and rendering it the most striking example of genome reduction in a microbial pathogen.
Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!
Subject Island | Start | End | Length | Subject Host Description | E-value | Bit score | Visual BLASTN | Visual BLASTP |
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NC_002677:332923* | 332923 | 354017 | 21095 | Mycobacterium leprae TN, complete genome | 0 | 41600 | BLASTN svg | BLASTP svg |
NC_002677:1822500 | 1822500 | 1841689 | 19190 | Mycobacterium leprae TN, complete genome | 0 | 761 | BLASTN svg | BLASTP svg |
NC_019950:481881 | 481881 | 506007 | 24127 | Mycobacterium canettii CIPT 140060008 complete genome | 3e-163 | 583 | BLASTN svg | BLASTP svg |
NC_015848:483500 | 483500 | 509988 | 26489 | Mycobacterium canettii CIPT 140010059, complete genome | 3e-163 | 583 | BLASTN svg | BLASTP svg |
NC_012207:477500 | 477500 | 500767 | 23268 | Mycobacterium bovis BCG str. Tokyo 172, complete genome | 3e-163 | 583 | BLASTN svg | BLASTP svg |
NC_008769:507000 | 507000 | 530434 | 23435 | Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome | 3e-163 | 583 | BLASTN svg | BLASTP svg |
NC_002945:476835 | 476835 | 500638 | 23804 | Mycobacterium bovis AF2122/97, complete genome | 3e-163 | 583 | BLASTN svg | BLASTP svg |
NC_000962:475816 | 475816 | 499619 | 23804 | Mycobacterium tuberculosis H37Rv, complete genome | 4e-162 | 579 | BLASTN svg | BLASTP svg |
NC_002755:472872 | 472872 | 496457 | 23586 | Mycobacterium tuberculosis CDC1551, complete genome | 4e-162 | 579 | BLASTN svg | BLASTP svg |
NC_009525:477093 | 477093 | 500929 | 23837 | Mycobacterium tuberculosis H37Ra, complete genome | 4e-162 | 579 | BLASTN svg | BLASTP svg |
NC_009565:479500 | 479500 | 502789 | 23290 | Mycobacterium tuberculosis F11, complete genome | 4e-162 | 579 | BLASTN svg | BLASTP svg |
NC_010612:835648 | 835648 | 862999 | 27352 | Mycobacterium marinum M, complete genome | 4e-119 | 436 | BLASTN svg | BLASTP svg |
NC_014814:1425500* | 1425500 | 1444351 | 18852 | Mycobacterium sp. Spyr1 chromosome, complete genome | 3e-30 | 141 | BLASTN svg | BLASTP svg |
NC_012522:2031786* | 2031786 | 2061572 | 29787 | Rhodococcus opacus B4, complete genome | 5e-29 | 137 | BLASTN svg | BLASTP svg |
NC_009077:4671417* | 4671417 | 4699507 | 28091 | Mycobacterium sp. JLS, complete genome | 8e-28 | 133 | BLASTN svg | BLASTP svg |
NC_009525:2635792* | 2635792 | 2658641 | 22850 | Mycobacterium tuberculosis H37Ra, complete genome | 5e-26 | 127 | BLASTN svg | BLASTP svg |
NC_008268:2313583* | 2313583 | 2344488 | 30906 | Rhodococcus sp. RHA1, complete genome | 7e-16 | 93.7 | BLASTN svg | BLASTP svg |
NC_008271:35909 | 35909 | 62461 | 26553 | Rhodococcus sp. RHA1 plasmid pRHL3, complete sequence | 7e-16 | 93.7 | BLASTN svg | BLASTP svg |
NC_013093:737737 | 737737 | 762228 | 24492 | Actinosynnema mirum DSM 43827, complete genome | 1e-14 | 89.7 | BLASTN svg | BLASTP svg |
NC_008271:140846 | 140846 | 166546 | 25701 | Rhodococcus sp. RHA1 plasmid pRHL3, complete sequence | 1e-14 | 89.7 | BLASTN svg | BLASTP svg |
NC_014814:1397429 | 1397429 | 1421567 | 24139 | Mycobacterium sp. Spyr1 chromosome, complete genome | 2e-13 | 85.7 | BLASTN svg | BLASTP svg |
NC_012704:652589* | 652589 | 676344 | 23756 | Corynebacterium kroppenstedtii DSM 44385, complete genome | 2e-13 | 85.7 | BLASTN svg | BLASTP svg |
NC_009077:4810379 | 4810379 | 4839610 | 29232 | Mycobacterium sp. JLS, complete genome | 7e-13 | 83.8 | BLASTN svg | BLASTP svg |
NC_010612:4501414* | 4501414 | 4524992 | 23579 | Mycobacterium marinum M, complete genome | 3e-12 | 81.8 | BLASTN svg | BLASTP svg |
NC_012590:1004816* | 1004816 | 1028331 | 23516 | Corynebacterium aurimucosum ATCC 700975, complete genome | 1e-11 | 79.8 | BLASTN svg | BLASTP svg |
NC_018581:3202281* | 3202281 | 3227026 | 24746 | Gordonia sp. KTR9 chromosome, complete genome | 1e-11 | 79.8 | BLASTN svg | BLASTP svg |
NC_009142:949510* | 949510 | 978142 | 28633 | Saccharopolyspora erythraea NRRL 2338, complete genome | 3e-09 | 71.9 | BLASTN svg | BLASTP svg |
NC_007516:2277910* | 2277910 | 2330102 | 52193 | Synechococcus sp. CC9605, complete genome | 2e-07 | 65.9 | BLASTN svg | BLASTP svg |
NC_015957:9801884 | 9801884 | 9824182 | 22299 | Streptomyces violaceusniger Tu 4113 chromosome, complete genome | 2e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_014158:2561441* | 2561441 | 2585255 | 23815 | Tsukamurella paurometabola DSM 20162 chromosome, complete genome | 2e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_014148:3368519* | 3368519 | 3392807 | 24289 | Planctomyces limnophilus DSM 3776 chromosome, complete genome | 2e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_015565:128350 | 128350 | 155119 | 26770 | Desulfotomaculum carboxydivorans CO-1-SRB chromosome, complete | 1e-05 | 60 | BLASTN svg | BLASTP svg |