Query: NC_004088:1291754 Yersinia pestis KIM, complete genome
Start: 1291754, End: 1314207, Length: 22454
Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria
General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.
Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!
Subject Island | Start | End | Length | Subject Host Description | E-value | Bit score | Visual BLASTN | Visual BLASTP |
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NC_008149:1221637 | 1221637 | 1243315 | 21679 | Yersinia pestis Nepal516, complete genome | 0 | 38120 | BLASTN svg | BLASTP svg |
NC_003143:2895617 | 2895617 | 2918099 | 22483 | Yersinia pestis CO92, complete genome | 0 | 38110 | BLASTN svg | BLASTP svg |
NC_008150:2785830 | 2785830 | 2808099 | 22270 | Yersinia pestis Antiqua, complete genome | 0 | 16650 | BLASTN svg | BLASTP svg |
NC_015224:1440283 | 1440283 | 1458496 | 18214 | Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome, | 2e-139 | 504 | BLASTN svg | BLASTP svg |
NC_020064:1150982* | 1150982 | 1170406 | 19425 | Serratia marcescens FGI94, complete genome | 4e-82 | 313 | BLASTN svg | BLASTP svg |
NC_012779:2064582 | 2064582 | 2091127 | 26546 | Edwardsiella ictaluri 93-146, complete genome | 2e-74 | 287 | BLASTN svg | BLASTP svg |
NC_013421:3237633 | 3237633 | 3259199 | 21567 | Pectobacterium wasabiae WPP163, complete genome | 8e-59 | 236 | BLASTN svg | BLASTP svg |
NC_009832:4269804 | 4269804 | 4296500 | 26697 | Serratia proteamaculans 568, complete genome | 6e-41 | 176 | BLASTN svg | BLASTP svg |
NC_008513:343540* | 343540 | 365176 | 21637 | Buchnera aphidicola str. Cc (Cinara cedri), complete genome | 1e-14 | 89.7 | BLASTN svg | BLASTP svg |
NC_004545:499709* | 499709 | 529218 | 29510 | Buchnera aphidicola str. Bp (Baizongia pistaciae), complete genome | 7e-13 | 83.8 | BLASTN svg | BLASTP svg |
NC_013592:804288 | 804288 | 834594 | 30307 | Dickeya dadantii Ech586, complete genome | 7e-13 | 83.8 | BLASTN svg | BLASTP svg |
NC_021150:1322000 | 1322000 | 1357157 | 35158 | Azotobacter vinelandii CA6, complete genome | 3e-12 | 81.8 | BLASTN svg | BLASTP svg |
NC_012560:1322000 | 1322000 | 1357145 | 35146 | Azotobacter vinelandii DJ, complete genome | 3e-12 | 81.8 | BLASTN svg | BLASTP svg |
NC_008595:2546696 | 2546696 | 2584803 | 38108 | Mycobacterium avium 104, complete genome | 7e-10 | 73.8 | BLASTN svg | BLASTP svg |
NC_002755:831397 | 831397 | 850054 | 18658 | Mycobacterium tuberculosis CDC1551, complete genome | 1e-08 | 69.9 | BLASTN svg | BLASTP svg |
NC_002945:831029 | 831029 | 853656 | 22628 | Mycobacterium bovis AF2122/97, complete genome | 1e-08 | 69.9 | BLASTN svg | BLASTP svg |
NC_008769:860670 | 860670 | 879696 | 19027 | Mycobacterium bovis BCG str. Pasteur 1173P2, complete genome | 1e-08 | 69.9 | BLASTN svg | BLASTP svg |
NC_009525:830513 | 830513 | 849219 | 18707 | Mycobacterium tuberculosis H37Ra, complete genome | 1e-08 | 69.9 | BLASTN svg | BLASTP svg |
NC_009565:833076 | 833076 | 851782 | 18707 | Mycobacterium tuberculosis F11, complete genome | 1e-08 | 69.9 | BLASTN svg | BLASTP svg |
NC_012207:831030 | 831030 | 853609 | 22580 | Mycobacterium bovis BCG str. Tokyo 172, complete genome | 1e-08 | 69.9 | BLASTN svg | BLASTP svg |
NC_012214:1212616 | 1212616 | 1236250 | 23635 | Erwinia pyrifoliae Ep1/96, complete genome | 1e-08 | 69.9 | BLASTN svg | BLASTP svg |
NC_013421:3117639* | 3117639 | 3140383 | 22745 | Pectobacterium wasabiae WPP163, complete genome | 1e-08 | 69.9 | BLASTN svg | BLASTP svg |
NC_014306:3006028* | 3006028 | 3042131 | 36104 | Erwinia billingiae Eb661, complete genome | 1e-08 | 69.9 | BLASTN svg | BLASTP svg |
NC_015633:1702000 | 1702000 | 1725373 | 23374 | Vibrio anguillarum 775 chromosome chromosome I, complete sequence | 1e-08 | 69.9 | BLASTN svg | BLASTP svg |
NC_009648:2465613* | 2465613 | 2497208 | 31596 | Klebsiella pneumoniae subsp. pneumoniae MGH 78578, complete genome | 4e-08 | 67.9 | BLASTN svg | BLASTP svg |
NC_014837:2758239* | 2758239 | 2778599 | 20361 | Pantoea sp. At-9b chromosome, complete genome | 4e-08 | 67.9 | BLASTN svg | BLASTP svg |
NC_015556:819503* | 819503 | 842901 | 23399 | Pseudomonas fulva 12-X chromosome, complete genome | 7e-07 | 63.9 | BLASTN svg | BLASTP svg |
NC_013956:1994970 | 1994970 | 2019706 | 24737 | Pantoea ananatis LMG 20103 chromosome, complete genome | 7e-07 | 63.9 | BLASTN svg | BLASTP svg |
NC_014121:3188928 | 3188928 | 3213287 | 24360 | Enterobacter cloacae subsp. cloacae ATCC 13047 chromosome, complete | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |
NC_013282:3781149 | 3781149 | 3804843 | 23695 | Cronobacter turicensis, complete genome | 3e-06 | 61.9 | BLASTN svg | BLASTP svg |