Pre_GI Gene

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Host: NC_012207 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_012207:831030 Mycobacterium bovis BCG str. Tokyo 172, complete genome

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Used for the production of BCG vaccine in Japan. Causative agent of classic bovine tuberculosis. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced. The pathology in cows is similar to the pathology of Mycobacterium tuberculosis in humans, with pulmonary TB leading to chronic debilitation, coughing, and further systemic spread to other organs. In addition, 1 to 2% of infected cows develop mycobacterial mastitis that results in shedding of the bacteria into the milk.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
831030831527498putative transcriptional regulatory proteinQuickGO ontologyBLASTP
831885832433549hypothetical proteinBLASTP
832638833486849hypothetical proteinBLASTP
833601834128528hypothetical proteinBLASTP
834359834673315transposaseQuickGO ontologyBLASTP
834815835333519PE-PGRS family proteinQuickGO ontologyBLASTP
835711836268558hypothetical proteinBLASTP
836265836771507putative transcriptional regulatory proteinQuickGO ontologyBLASTP
836979837506528hypothetical proteinBLASTP
8375268399192394PE-PGRS family proteinQuickGO ontologyBLASTP
8403188429992682PE-PGRS family proteinQuickGO ontologyBLASTP
843090843347258hypothetical proteinBLASTP
843371843799429hypothetical proteinBLASTP
843880844017138hypothetical proteinBLASTP
844176844421246hypothetical proteinBLASTP
844490845374885putative 3-hydroxyisobutyrate dehydrogenaseQuickGO ontologyBLASTP
8453858465571173putative acyl-CoA dehydrogenaseQuickGO ontologyBLASTP
8465648480961533putative methylmalonate-semialdehyde dehydrogenaseQuickGO ontologyBLASTP
8483028500561755PE-PGRS family proteinQuickGO ontologyBLASTP
8502468521831938PPE family proteinQuickGO ontologyBLASTP
852485852670186putative transposaseQuickGO ontologyBLASTP
852884853609726hypothetical proteinBLASTP