Pre_GI: BLASTP Hits

Query: NC_011149:4390315:4392258 Salmonella enterica subsp. enterica serovar Agona str. SL483,

Start: 4392258, End: 4392701, Length: 444

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Salmonella enterica subsp. enterica serovar Agona causes gastroenteritis in humans and is also pathogenic to swine and other food animals. This serovar is able to contain the Salmonella genomic island 1 multidrug resistance gene cluster. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.