Pre_GI Gene

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Host: NC_011080 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_011080:4461851 Salmonella enterica subsp. enterica serovar Newport str. SL254,

Host Lineage: Salmonella enterica; Salmonella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: The SL254 strain is an MDR strain from one of two distinct lineages of the Newport serovar. Salmonella enterica subsp. enterica serovar Newport is common worldwide. Outbreak investigations and targeted studies have identified dairy cattle as the main reservoir this serotype. Antimicrobial resistance (Newport MDR-AmpC) is particularly problematic in this serotype, and the prevalence of Newport MDR-AmpC isolates from humans in the United States has increased from 0% during 1996-1997 to 26% in 2001. MDR strains have been recorded as resistant to ampicillin, chloramphenicol, streptomycin, sulphonamides and tetracycline (ACSSuT) and many of these strains show intermediate or full resistance to third-generation cephalosporins, kanamycin, potentiated sulphonamides, and gentamicin. This group of Enterobactericiae have pathogenic characteristics and are one of the most common causes of enteric infections (food poisoning) worldwide. They were named after the scientist Dr. Daniel Salmon who isolated the first organism, Salmonella choleraesuis, from the intestine of a pig. The presence of several pathogenicity islands (PAIs) that encode various virulence factors allows Salmonella spp. to colonize and infect host organisms. There are two important PAIs, Salmonella pathogenicity island 1 and 2 (SPI-1 and SPI-2) that encode two different type III secretion systems for the delivery of effector molecules into the host cell that result in internalization of the bacteria which then leads to systemic spread.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
44618514462564714had superfamily subfamily iiib phosphataseQuickGO ontologyBLASTP
44626934463109417hypothetical proteinBLASTP
44631124463468357protein YjbRQuickGO ontologyBLASTP
44634694463807339hypothetical proteinBLASTP
44637944464237444hypothetical proteinBLASTP
446438144672062826excinuclease ABC A subunitQuickGO ontologyBLASTP
44674544467984531single-stranded DNA-binding proteinQuickGO ontologyBLASTP
44681944468328135hypothetical proteinBLASTP
44683754468515141hypothetical proteinBLASTP
44690254469657633hypothetical proteinBLASTP
446965444710421389putative integral membrane proteinQuickGO ontologyBLASTP
44714254472351927putative type-I secretion proteinQuickGO ontologyBLASTP
447237544736251251hypothetical proteinBLASTP
4473642449032116680large repetitive proteinQuickGO ontologyBLASTP