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Query: NC_008258:269806:270885 Shigella flexneri 5 str. 8401, complete genome

Start: 270885, End: 271433, Length: 549

Host Lineage: Shigella flexneri; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This genus is named for the Japanese scientist (Shiga) who discovered them in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. Shigella spp. are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, and over 1 million deaths worldwide are attributed to them. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that require very few cells in order to cause disease. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism, along with Shigella sonnei, is the major cause of shigellosis in industrialized countries and is responsible for endemic infections.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_011750:2928990:294209829420982942646549Escherichia coli IAI39 chromosome, complete genomeputative baseplate assembly phage protein2e-101367
NC_011742:2823000:284261128426112843159549Escherichia coli S88 chromosome, complete genomebaseplate assembly phage protein6e-101365
NC_008563:2909945:292530129253012925849549Escherichia coli APEC O1, complete genomebacteriophage V tail protein6e-101365
NC_007946:2894793:291027429102742910822549Escherichia coli UTI89, complete genomebacteriophage V tail protein6e-101365
NC_011740:621408:622487622487623035549Escherichia fergusonii ATCC 35469, complete genomeputative baseplate assembly phage protein7e-101365
NC_009436:2776410:279203427920342792576543Enterobacter sp. 638, complete genomephage baseplate assembly protein V1e-78291
NC_011205:2137696:215301821530182153551534Salmonella enterica subsp. enterica serovar Dublin str. CT_02021853bacteriophage Mu Gp45 protein1e-57222
NC_016810:2027311:204599420459942046527534Salmonella enterica subsp. enterica serovar Typhimurium strputative bacteriophage baseplate protein1e-57222
NC_016856:2085283:209983120998312100364534Salmonella enterica subsp. enterica serovar Typhimurium str. 14028Sputative base plate assembly protein1e-57222
NC_016857:2027311:204599420459942046527534Salmonella enterica subsp. enterica serovar Typhimurium str. ST4/74putative base plate assembly protein1e-57222
NC_016863:2029340:204802320480232048556534Salmonella enterica subsp. enterica serovar Typhimurium str. UK-1hypothetical protein1e-57222
NC_017046:2026672:204535520453552045888534Salmonella enterica subsp. enterica serovar Typhimurium str. 798bacteriophage baseplate protein1e-57222
NC_011094:2115750:213167621316762132209534Salmonella enterica subsp. enterica serovar Schwarzengrund strbacteriophage Mu Gp45 protein2e-57221
NC_010102:1779707:180427918042791804812534Salmonella enterica subsp. enterica serovar Paratyphi B str. SPB7,hypothetical protein2e-57221
NC_011294:2009388:202471120247112025244534Salmonella enterica subsp. enterica serovar Enteritidis strphage baseplate protein7e-57219
NC_007712:1182518:119662311966231197189567Sodalis glossinidius str. 'morsitans', complete genomehypothetical protein1e-34145
NC_007712:4023516:403477740347774035328552Sodalis glossinidius str. 'morsitans', complete genomephage assembly protein6e-32136
NC_015733:1398083:139808313980831398583501Pseudomonas putida S16 chromosome, complete genomePhage assembly protein2e-21102
NC_002947:4362271:438590643859064386406501Pseudomonas putida KT2440, complete genomephage assembly protein, putative5e-21100
NC_002937:255790:256925256925257563639Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough, completephage baseplate assembly protein V, putative8e-2096.7
NC_002937:2933000:295332229533222953960639Desulfovibrio vulgaris subsp. vulgaris str. Hildenborough, completephage baseplate assembly protein V, putative2e-1995.1
NC_009800:2049346:207211820721182072699582Escherichia coli HS, complete genomebacteriophage Mu Gp45 protein8e-1683.2
NC_014228:3282500:331026233102623310807546Xenorhabdus nematophila ATCC 19061, complete genomeputative baseplate assembly protein7e-1580.1
NC_002927:3827211:383902838390283839669642Bordetella bronchiseptica RB50, complete genomehypothetical protein2e-0962
NC_000907:1568867:158827715882771588825549Haemophilus influenzae Rd KW20, complete genomehypothetical protein1e-0859.7
NC_016628:373815:395011395011395586576Vibrio furnissii NCTC 11218 chromosome 2, complete sequencephage baseplate assembly protein6e-0857.4
NC_008014:112000:131586131586132182597Lawsonia intracellularis PHE/MN1-00 plasmid 3, complete sequencehypothetical protein1e-0756.2