Pre_GI Gene

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Host: NC_000907 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_000907:1568867 Haemophilus influenzae Rd KW20, complete genome

Host Lineage: Haemophilus influenzae; Haemophilus; Pasteurellaceae; Pasteurellales; Proteobacteria; Bacteria

General Information: Small, nonmotile, Gram-negative bacterium whose only natural host is human. It lacks an important fimbrial gene cluster that is important for virulence as compared to type b strains and was the first microbe to ever be sequenced. A group of organisms that are either obligate parasites or commensal organisms found in animal mucous membranes. Almost all species require the presence of important growth factors found in the blood of their hosts, including either X factor (protoporphyrin IX or heme) or V factor (nicotinamide adenine dinucleotide (NAD or NADP)). This organism was first isolated in the 1890s during an influenza pandemic by Pfeiffer, and was originally thought to be the source of influenza, although later it was shown to be a secondary pathogen and may be synergistic with the influenza virus. This bacterium is one of the leading causes of meningitis in young children, and it may also cause septicemia, otitis media (inflammation of the middle ear), sinusitis (inflammation of the sinus cavity) and chronic bronchitis. It is highly adapted to its human host and typically lives in the nasopharynx and is a major cause of lower respiratory infections in infants and small children in developing countries (type 1b strain), although vaccine use has resulted in the decline of infections. The encapsulated organism can penetrate the blood and avoid both phagocytosis and complement-mediated lysis. All known strains produce neuraminidase and an IgA protease as well as fimbrial adhesins for attachment.


StartEndLengthCDS descriptionQuickGO ontologyBLASTP
15693091569815507hypothetical proteinBLASTP
15698971570181285hypothetical proteinBLASTP
15701661570441276N-acetylmuramoyl-L-alanine amidaseQuickGO ontologyBLASTP
15704481570708261hypothetical proteinBLASTP
15707051570959255hypothetical protein
15710771571304228hypothetical proteinBLASTP
15712111571630420hypothetical proteinBLASTP
15716351571943309hypothetical proteinBLASTP
15719551572524570hypothetical proteinBLASTP
157252415740501527hypothetical proteinBLASTP
157406215756241563hypothetical proteinBLASTP
157571515769591245hypothetical proteinBLASTP
15770971577537441G proteinQuickGO ontologyBLASTP
157776815788351068I proteinQuickGO ontologyBLASTP
15788351579761927hypothetical proteinBLASTP
15798441580101258hypothetical proteinBLASTP
15801131580229117hypothetical protein
15802321580657426hypothetical proteinBLASTP
15806571581208552hypothetical proteinBLASTP
15812211581412192hypothetical proteinBLASTP
158141215828751464sheath protein gpLQuickGO ontologyBLASTP
15828851583241357hypothetical proteinBLASTP
15832541583637384hypothetical proteinBLASTP
158371815856131896monofunctional biosynthetic peptidoglycan transglycosylaseQuickGO ontologyBLASTP
15856131586980136864 kDa virion proteinQuickGO ontologyBLASTP
15882771588825549hypothetical proteinBLASTP
15888341589241408hypothetical proteinBLASTP
158924115903081068hypothetical proteinBLASTP
15903401590900561hypothetical proteinBLASTP
159090015927711872hypothetical proteinBLASTP
15932551593374120hypothetical protein
15933851594275891hypothetical proteinBLASTP
15948291595566738molybdate-binding periplasmic proteinQuickGO ontologyBLASTP
159575315971831431ADP-heptose synthaseQuickGO ontologyBLASTP
15972801598215936lipid A biosynthesis lauroyl acyltransferaseQuickGO ontologyBLASTP
159828916001871899DNA topoisomerase IV subunit BQuickGO ontologyBLASTP
160025416024972244DNA topoisomerase IV subunit AQuickGO ontologyBLASTP
160253916037531215glutamate permeaseQuickGO ontologyBLASTP