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Query: NC_002945:476835:477698 Mycobacterium bovis AF2122/97, complete genome

Start: 477698, End: 478339, Length: 642

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This strain is a fully virulent strain that was isolated in 1997 in the UK from a cow suffering necrotic lesions in lung and bronchomediastinal lymph nodes. The strain was also reported to infect and persist in badgers that are considered to be a significant source of bovine infection. Causative agent of classic bovine tuberculosis. This genus comprises a number of Gram-positive, acid-fast, rod-shaped aerobic bacteria and is the only member of the family Mycobacteriaceae within the order Actinomycetales. Like other closely related Actinomycetales, such as Nocardia and Corynebacterium, mycobacteria have unusually high genomic DNA GC content and are capable of producing mycolic acids as major components of their cell wall. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_017026:476500:476979476979477620642Mycobacterium tuberculosis RGTB327 chromosome, complete genomehypothetical protein6e-93339
NC_008769:507000:507494507494508135642Mycobacterium bovis BCG str. Pasteur 1173P2, complete genomeputative secreted protein6e-93339
NC_012207:477500:477827477827478468642Mycobacterium bovis BCG str. Tokyo 172, complete genomeputative secreted protein6e-93339
NC_002755:472872:476770476770477411642Mycobacterium tuberculosis CDC1551, complete genomehypothetical protein6e-93339
NC_009525:477093:477989477989478630642Mycobacterium tuberculosis H37Ra, complete genomeputative secreted protein6e-93339
NC_009565:479500:479849479849480490642Mycobacterium tuberculosis F11, complete genomehypothetical secreted protein6e-93339
NC_000962:475816:476679476679477320642Mycobacterium tuberculosis H37Rv, complete genomePOSSIBLE SECRETED PROTEIN6e-93339
NC_012943:476500:476938476938477579642Mycobacterium tuberculosis KZN 1435 chromosome, complete genomehypothetical protein6e-93339
NC_016768:476500:476938476938477579642Mycobacterium tuberculosis KZN 4207 chromosome, complete genomesecreted protein6e-93339
NC_016804:477500:477828477828478469642Mycobacterium bovis BCG str. Mexico chromosome, complete genomehypothetical protein6e-93339
NC_019950:481881:483017483017483658642Mycobacterium canettii CIPT 140060008 complete genomeConserved secreted protein of unknown function2e-92338
NC_015848:483500:483968483968484609642Mycobacterium canettii CIPT 140010059, complete genomeputative secreted protein2e-92338