Pre_GI: BLASTN Hits

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Query: NC_005945:1459357 Bacillus anthracis str. Sterne, complete genome

Start: 1459357, End: 1483613, Length: 24257

Host Lineage: Bacillus anthracis; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain carries the anthrax toxin plasmid pXO1 but not the capsule plasmid pXO2 and is therefore avirulent but toxigenic. It is the counterpart to the Pasteur strain that carries pXO2 but not pXO1. This strain is often used for vaccine development. Under starvation conditions this group of bacteria initiate a pathway that leads to endospore formation, a process that is thoroughly studied and is a model system for prokaryotic development and differentiation. Spores are highly resistant to heat, cold, dessication, radiation, and disinfectants, and enable the organism to persist in otherwise inhospitable environments. Under more inviting conditions the spores germinate to produce vegetative cells. This organism was the first to be shown to cause disease by Dr. Louis Pasteur (the organism, isolated from sick animals, was grown in the laboratory and then used to infect healthy animals and make them sick). This organism was also the first for which an attenuated strain was developed as a vaccine. Herbivorous animals become infected with the organism when they ingest spores from the soil whereas humans become infected when they come into contact with a contaminated animal. PA/LF and PA/EF complexes are internalized by host cells where the LF (metalloprotease) and EF (calmodulin-dependent adenylate cyclase) components act. At high levels LF induces cell death and release of the bacterium while EF increases host susceptibility to infection and promotes fluid accumulation in the cells.




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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_007530:14594121459412148366224251Bacillus anthracis str. 'Ames Ancestor', complete genome018120BLASTN svgBLASTP svg
NC_011772:21660002166000218832022321Bacillus cereus G9842, complete genome6e-29137BLASTN svgBLASTP svg
NC_005957:21960002196000221809922100Bacillus thuringiensis serovar konkukian str. 97-27, complete9e-22113BLASTN svgBLASTP svg
NC_014335:21514042151404217409922696Bacillus cereus biovar anthracis str. CI chromosome, complete2e-19105BLASTN svgBLASTP svg
NC_012472:22400002240000226209922100Bacillus cereus 03BB102, complete genome2e-19105BLASTN svgBLASTP svg
NC_007530:21759672175967219810122135Bacillus anthracis str. 'Ames Ancestor', complete genome2e-19105BLASTN svgBLASTP svg
NC_005945:21758712175871219809922229Bacillus anthracis str. Sterne, complete genome2e-19105BLASTN svgBLASTP svg
NC_003997:21758432175843219809922257Bacillus anthracis str. Ames, complete genome2e-19105BLASTN svgBLASTP svg