Pre_GI Gene

Some Help

Host: NC_014335 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_014335:2151404 Bacillus cereus biovar anthracis str. CI chromosome, complete

Host Lineage: Bacillus cereus; Bacillus; Bacillaceae; Bacillales; Firmicutes; Bacteria

General Information: This strain probably caused lethal anthrax in chimpanzee Leo in the rainforest of the Tai National Park, Cote d'Ivoire. It belongs to a collection of genetically closely related bacteria, isolated in 2001 and 2002 from deceased wild chimpanzees living in this rain forest area. An autopsy showed symptoms typical of anthrax, but the bacterium isolated was motile, unlike B.anthracis. This organism is a soil-dwelling opportunistic pathogen that causes food poisoning in infected individuals. The rapid onset is characterized by nausea and vomiting while the late onset is characterized by diarrhea and abdominal pain. The emetic disease is caused by a small stable dodecadepsipeptide cerulide whereas the diarrheal disease is caused by a heat labile enterotoxin. Some strains produce a potent cytotoxin that forms a pore in the membrane of eukaryotic cells and causes necrotic enteritis (death of intestinal epithelial cells) while the unique tripartite membrane lytic toxin hemolysin BL contributes to the diarrheal disease and destructive infections of the eye.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
21514042152111708short chain dehydrogenaseQuickGO ontologyBLASTP
21521792152490312hypothetical proteinBLASTP
21526772152937261hypothetical proteinBLASTP
215368221561862505penicillin-binding protein 1AQuickGO ontologyBLASTP
215680121579461146glycerol-3-phosphate transporterQuickGO ontologyBLASTP
21579622158252291hypothetical proteinBLASTP
215865121597721122citrate synthaseQuickGO ontologyBLASTP
2159871216130714372-methylcitrate dehydrataseQuickGO ontologyBLASTP
21613262162234909carboxyvinyl-carboxyphosphonate phosphorylmutaseQuickGO ontologyBLASTP
216238921640981710acyl-CoA dehydrogenaseQuickGO ontologyBLASTP
216411521650058913-hydroxyisobutyrate dehydrogenaseQuickGO ontologyBLASTP
216504221665021461methylmalonic acid semialdehyde dehydrogenaseQuickGO ontologyBLASTP
21664312167204774homoserinethreonine efflux proteinQuickGO ontologyBLASTP
216738821684431056enoyl-CoA hydrataseQuickGO ontologyBLASTP
21687602169017258hypothetical proteinBLASTP
21692012169440240hypothetical proteinBLASTP
216945621706131158exonuclease SbcDQuickGO ontologyBLASTP
217061021736993090exonuclease SbcCQuickGO ontologyBLASTP