Pre_GI Island

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n1_4mer:GRV/n1_4mer:RV = (Global Relative Variance of OU patterns) / (Local Relative Variance of OU patterns)

n0_4mer:D = Distance between local and global OU patterns

n0_4mer:PS = Distance between 2 strands of same DNA molecule

Selected loci indicated by large D, increased GRV associated with decreased RV and moderate increase in PS

NC_020207: Enterococcus faecium NRRL B-2354, complete genome

NCBI: NC_020207

Host Lineage: Enterococcus faecium; Enterococcus; Enterococcaceae; Lactobacillales; Firmicutes; Bacteria

General Information: This genera consists of organisms typically found in the intestines of mammals, although through fecal contamination they can appear in sewage, soil, and water. They cause a number of infections that are becoming increasingly a problem due to the number of antibiotic resistance mechanisms these organisms have picked up. Both Enterococcus faecalis and Enterococcus faecium cause similar diseases in humans, and are mainly distinguished by their metabolic capabilities. This opportunistic pathogen causes a range of infections similar to those observed with Enterococcus faecalis, including urinary tract infections, bacteremia (bacteria in the blood), and infective endocarditis (inflammation of the membrane surrounding the heart). Hospital-acquired infections from this organism are on the rise due to the emergence of antiobiotic resistance strains and has led to the rise of vancomycin-resistant Staphylococcus aureus strains due to the horizontal transfer of Enterococcus antibiotic resistance genes. Little is known about the virulence mechanisms in this organism, but the genome does encode an esp gene for the surface adhesin. Vancomycin resistant isolates are more typically Enterococcus faecium than Enterococcus faecalis.

Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

#StartEndLengthIsland TextGRV_RVDPSNeighboursClusterSub ClusterBLASTNKey Word ConfirmationOther DB ConfirmationDownload Island
155931058209922790Island text2.0493824.348644.6213Neighbours21BLASTN+559310.gbk
2843822*87015126330Island text1.4347120.987412.7117Neighbours21BLASTN843822.gbk
31170000118959919600Island text3.6079723.85613.6629Neighbours21BLASTN+1170000.gbk
41346579138861142033Island text1.9418620.459434.0212Neighbours21BLASTN+1346579.gbk
51614000*163759923600Island text2.6346527.138945.0524Neighbours21BLASTN+1614000.gbk
61795993181911423122Island text1.8126120.972313.4502Neighbours21BLASTN+1795993.gbk
71872000190209930100Island text1.9163822.740215.4071Neighbours21BLASTN+1872000.gbk
81906803192509918297Island text1.4860120.239523.8397Neighbours21BLASTN+1906803.gbk
92240115*226013620022Island text2.2159222.717310.8933Neighbours21BLASTN+2240115.gbk
102575808*259723221425Island text2.7326719.73939.8648Neighbours21BLASTN+2575808.gbk