Pre_GI Gene

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Host: NC_020207 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_020207:843822 Enterococcus faecium NRRL B-2354, complete genome

Host Lineage: Enterococcus faecium; Enterococcus; Enterococcaceae; Lactobacillales; Firmicutes; Bacteria

General Information: This genera consists of organisms typically found in the intestines of mammals, although through fecal contamination they can appear in sewage, soil, and water. They cause a number of infections that are becoming increasingly a problem due to the number of antibiotic resistance mechanisms these organisms have picked up. Both Enterococcus faecalis and Enterococcus faecium cause similar diseases in humans, and are mainly distinguished by their metabolic capabilities. This opportunistic pathogen causes a range of infections similar to those observed with Enterococcus faecalis, including urinary tract infections, bacteremia (bacteria in the blood), and infective endocarditis (inflammation of the membrane surrounding the heart). Hospital-acquired infections from this organism are on the rise due to the emergence of antiobiotic resistance strains and has led to the rise of vancomycin-resistant Staphylococcus aureus strains due to the horizontal transfer of Enterococcus antibiotic resistance genes. Little is known about the virulence mechanisms in this organism, but the genome does encode an esp gene for the surface adhesin. Vancomycin resistant isolates are more typically Enterococcus faecium than Enterococcus faecalis.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
843822844766945Cell envelope-associated transcriptional attenuator LytR-CpsA-PsrQuickGO ontologyBLASTP
844782845561780Tyrosine-protein kinase transmembrane modulator EpsCQuickGO ontologyBLASTP
845574846272699Tyrosine-protein kinase EpsDQuickGO ontologyBLASTP
846300847064765Manganese-dependent protein-tyrosine phosphataseQuickGO ontologyBLASTP
8470778488941818UDP-N-acetylglucosamine 4 6-dehydrataseQuickGO ontologyBLASTP
848905849519615Undecaprenyl-phosphate galactosephosphotransferaseQuickGO ontologyBLASTP
849516850298783UDP-glucose 4-epimeraseQuickGO ontologyBLASTP
850361851182822glycosyl transferase family 2QuickGO ontologyBLASTP
8511858523061122YveSQuickGO ontologyBLASTP
8523038533821080hypothetical proteinBLASTP
8533958545041110capsular polysaccharide biosynthesis proteinQuickGO ontologyBLASTP
854494855450957putative glycosyltransferaseQuickGO ontologyBLASTP
855454856185732polysaccharide biosynthesis protein CpsMQuickGO ontologyBLASTP
8561968576261431Membrane protein involved in the export of O-antigen teichoic acid lipoteichoic acidQuickGO ontologyBLASTP
858382859131750Phosphosugar-binding transcriptional repressor RpiR familyQuickGO ontologyBLASTP
859274860224951Tagatose-6-phosphate kinase 1-phosphofructokinaseQuickGO ontologyBLASTP
8602068616691464PTS system galactose-inducible IIB component PTS system galactose-inducible IIC componentQuickGO ontologyBLASTP
862126863100975tagatose-1 6-diphosphate aldolaseQuickGO ontologyBLASTP
863279864229951Inner membrane protein translocase component YidC OxaA proteinQuickGO ontologyBLASTP
864667864942276putative nucleoside phosphataseQuickGO ontologyBLASTP
865049865813765rRNA methylaseQuickGO ontologyBLASTP
865936866439504HD family hydrolaseQuickGO ontologyBLASTP
8689528701511200hypothetical proteinBLASTP