Pre_GI Gene

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Host: NC_020207 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_020207:1795993 Enterococcus faecium NRRL B-2354, complete genome

Host Lineage: Enterococcus faecium; Enterococcus; Enterococcaceae; Lactobacillales; Firmicutes; Bacteria

General Information: This genera consists of organisms typically found in the intestines of mammals, although through fecal contamination they can appear in sewage, soil, and water. They cause a number of infections that are becoming increasingly a problem due to the number of antibiotic resistance mechanisms these organisms have picked up. Both Enterococcus faecalis and Enterococcus faecium cause similar diseases in humans, and are mainly distinguished by their metabolic capabilities. This opportunistic pathogen causes a range of infections similar to those observed with Enterococcus faecalis, including urinary tract infections, bacteremia (bacteria in the blood), and infective endocarditis (inflammation of the membrane surrounding the heart). Hospital-acquired infections from this organism are on the rise due to the emergence of antiobiotic resistance strains and has led to the rise of vancomycin-resistant Staphylococcus aureus strains due to the horizontal transfer of Enterococcus antibiotic resistance genes. Little is known about the virulence mechanisms in this organism, but the genome does encode an esp gene for the surface adhesin. Vancomycin resistant isolates are more typically Enterococcus faecium than Enterococcus faecalis.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
179599317971591167Cyclopropane-fatty-acyl-phospholipid synthaseQuickGO ontologyBLASTP
17973101798125816Maltodextrose utilization protein MalAQuickGO ontology
17981381798989852Maltose maltodextrin ABC transporter permease protein MalGQuickGO ontologyBLASTP
179899218002931302Maltose maltodextrin ABC transporter permease protein MalFQuickGO ontologyBLASTP
180044018016991260Maltose maltodextrin ABC transporter substrate binding periplasmic protein MalEQuickGO ontologyBLASTP
180180118035671767NeopullulanaseQuickGO ontologyBLASTP
18040341804804771hypothetical proteinBLASTP
18049041805338435transcriptional regulator MerR familyQuickGO ontologyBLASTP
18055191805929411Organic hydroperoxide resistance proteinQuickGO ontologyBLASTP
18059861806426441Organic hydroperoxide resistance transcriptional regulator MarR familyQuickGO ontologyBLASTP
180657718076141038hypothetical proteinBLASTP
180774018090531314hypothetical protein
180920118107541554hypothetical protein
181086218119441083Mannonate dehydrataseQuickGO ontologyBLASTP
181193518135811647D-mannonate oxidoreductaseQuickGO ontologyBLASTP
18137651814427663regulatory protein GntR Bacterial regulatory protein GntRQuickGO ontologyBLASTP
18145711815134564Alkyl hydroperoxide reductase protein CQuickGO ontologyBLASTP
181514418166731530Alkyl hydroperoxide reductase protein FQuickGO ontologyBLASTP
18168301817180351hypothetical proteinBLASTP
18172791817809531hypothetical protein
181796318191141152Na H antiporterQuickGO ontologyBLASTP