Pre_GI Gene

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Host: NC_020207 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_020207:559310 Enterococcus faecium NRRL B-2354, complete genome

Host Lineage: Enterococcus faecium; Enterococcus; Enterococcaceae; Lactobacillales; Firmicutes; Bacteria

General Information: This genera consists of organisms typically found in the intestines of mammals, although through fecal contamination they can appear in sewage, soil, and water. They cause a number of infections that are becoming increasingly a problem due to the number of antibiotic resistance mechanisms these organisms have picked up. Both Enterococcus faecalis and Enterococcus faecium cause similar diseases in humans, and are mainly distinguished by their metabolic capabilities. This opportunistic pathogen causes a range of infections similar to those observed with Enterococcus faecalis, including urinary tract infections, bacteremia (bacteria in the blood), and infective endocarditis (inflammation of the membrane surrounding the heart). Hospital-acquired infections from this organism are on the rise due to the emergence of antiobiotic resistance strains and has led to the rise of vancomycin-resistant Staphylococcus aureus strains due to the horizontal transfer of Enterococcus antibiotic resistance genes. Little is known about the virulence mechanisms in this organism, but the genome does encode an esp gene for the surface adhesin. Vancomycin resistant isolates are more typically Enterococcus faecium than Enterococcus faecalis.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
5593105611481839Type III restriction-modification system methylation subunitQuickGO ontologyBLASTP
561148562071924hypothetical protein
562068562643576hypothetical protein
5626435657533111Type III restriction enzyme res subunit DEAD DEAH box helicaseQuickGO ontologyBLASTP
5657785671391362hypothetical proteinBLASTP
5670935681121020hypothetical proteinBLASTP
568392568538147site-specific recombinase phage integrase familyQuickGO ontologyBLASTP
569181569621441hypothetical proteinBLASTP
569735569971237hypothetical proteinBLASTP
570119570325207hypothetical proteinBLASTP
571431571586156hypothetical protein
5720045735001497hypothetical proteinBLASTP
580697581527831Sortase A LPXTG specificQuickGO ontologyBLASTP