Pre_GI Gene

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Host: NC_020207 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_020207:1346579 Enterococcus faecium NRRL B-2354, complete genome

Host Lineage: Enterococcus faecium; Enterococcus; Enterococcaceae; Lactobacillales; Firmicutes; Bacteria

General Information: This genera consists of organisms typically found in the intestines of mammals, although through fecal contamination they can appear in sewage, soil, and water. They cause a number of infections that are becoming increasingly a problem due to the number of antibiotic resistance mechanisms these organisms have picked up. Both Enterococcus faecalis and Enterococcus faecium cause similar diseases in humans, and are mainly distinguished by their metabolic capabilities. This opportunistic pathogen causes a range of infections similar to those observed with Enterococcus faecalis, including urinary tract infections, bacteremia (bacteria in the blood), and infective endocarditis (inflammation of the membrane surrounding the heart). Hospital-acquired infections from this organism are on the rise due to the emergence of antiobiotic resistance strains and has led to the rise of vancomycin-resistant Staphylococcus aureus strains due to the horizontal transfer of Enterococcus antibiotic resistance genes. Little is known about the virulence mechanisms in this organism, but the genome does encode an esp gene for the surface adhesin. Vancomycin resistant isolates are more typically Enterococcus faecium than Enterococcus faecalis.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
134657913477181140Mannitol-1-phosphate 5-dehydrogenaseQuickGO ontologyBLASTP
13477301348161432PTS system mannitol-specific cryptic IIA componentQuickGO ontologyBLASTP
134817513496201446PTS system mannitol-specific cryptic IIB IIC componentQuickGO ontologyBLASTP
134990613515311626hypothetical proteinBLASTP
13517521351892141hypothetical protein
13521641352517354hypothetical protein
135330313547991497hypothetical proteinBLASTP
13571251357448324hypothetical protein
135743813595312094hypothetical proteinBLASTP
135957113616372067hypothetical proteinBLASTP
13617801362013234hypothetical protein
13620011362954954Putative stomatin prohibitin-family membrane protease subunit YbbKQuickGO ontologyBLASTP
13631971363925729Transcriptional regulatorQuickGO ontologyBLASTP
136445613658621407hypothetical proteinBLASTP
13658851366805921Inosine-uridine preferring nucleoside hydrolaseQuickGO ontologyBLASTP
13671011367940840hypothetical proteinBLASTP
136811513699201806Transcriptional antiterminator of lichenan operon BglG familyQuickGO ontologyBLASTP
137007913716861608major facilitator superfamilyQuickGO ontologyBLASTP
137168313733651683Amidohydrolase proteinQuickGO ontologyBLASTP
13734871374440954Integrase recombinase core familyQuickGO ontologyBLASTP
137539513766871293D-glycerate transporter predictedQuickGO ontologyBLASTP
137678813779331146Glycerate kinaseQuickGO ontologyBLASTP
137862813796411014Sugar diacid utilization regulator SdaRQuickGO ontologyBLASTP
137979313822102418mcrBQuickGO ontologyBLASTP
138220313835101308hypothetical proteinBLASTP
13844941384658165hypothetical protein
13858311386568738Beta-glucoside bgl operon antiterminator BglG familyQuickGO ontologyBLASTP
138675513886111857PTS system beta-glucoside-specific IIA IIB IIC componentQuickGO ontologyBLASTP