Pre_GI Gene

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Host: NC_020207 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_020207:2240115 Enterococcus faecium NRRL B-2354, complete genome

Host Lineage: Enterococcus faecium; Enterococcus; Enterococcaceae; Lactobacillales; Firmicutes; Bacteria

General Information: This genera consists of organisms typically found in the intestines of mammals, although through fecal contamination they can appear in sewage, soil, and water. They cause a number of infections that are becoming increasingly a problem due to the number of antibiotic resistance mechanisms these organisms have picked up. Both Enterococcus faecalis and Enterococcus faecium cause similar diseases in humans, and are mainly distinguished by their metabolic capabilities. This opportunistic pathogen causes a range of infections similar to those observed with Enterococcus faecalis, including urinary tract infections, bacteremia (bacteria in the blood), and infective endocarditis (inflammation of the membrane surrounding the heart). Hospital-acquired infections from this organism are on the rise due to the emergence of antiobiotic resistance strains and has led to the rise of vancomycin-resistant Staphylococcus aureus strains due to the horizontal transfer of Enterococcus antibiotic resistance genes. Little is known about the virulence mechanisms in this organism, but the genome does encode an esp gene for the surface adhesin. Vancomycin resistant isolates are more typically Enterococcus faecium than Enterococcus faecalis.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
22401152240819705Two-component response regulator SA14-24QuickGO ontologyBLASTP
22410092241869861Hypothetical protein DUF194 DegV familyQuickGO ontologyBLASTP
22418562242428573hypothetical proteinBLASTP
2242806224287873tRNA-LysQuickGO ontology
22433752243608234hypothetical protein
22437582244279522hypothetical proteinBLASTP
224428122453151035Protease IVQuickGO ontologyBLASTP
224534822466461299Bacteriocin export accessory proteinQuickGO ontologyBLASTP
224673222488852154ABC transporterQuickGO ontologyBLASTP
22491432249379237hypothetical protein
22493982249613216bacteriocin-like proteinQuickGO ontology
22503162251068753Response regulator of the LytR AlgR familyQuickGO ontologyBLASTP
225108322523661284putative signal transduction protein and ATPaseQuickGO ontologyBLASTP
22526562252994339putative immunity proteinQuickGO ontology
225356022552871728Glycine betaine ABC transport permease OpuABCQuickGO ontologyBLASTP
225528022564731194Glycine betaine ABC transport system ATP-binding protein OpuAAQuickGO ontologyBLASTP
22566602257304645transcriptional regulator GntR familyQuickGO ontologyBLASTP
22573982257532135hypothetical protein
225753422596662133Ferrous iron transport protein BQuickGO ontologyBLASTP
22596632260136474ferrous iron transport protein AQuickGO ontologyBLASTP