Pre_GI Island

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n1_4mer:GRV/n1_4mer:RV = (Global Relative Variance of OU patterns) / (Local Relative Variance of OU patterns)

n0_4mer:D = Distance between local and global OU patterns

n0_4mer:PS = Distance between 2 strands of same DNA molecule

Selected loci indicated by large D, increased GRV associated with decreased RV and moderate increase in PS

NC_013016: Neisseria meningitidis alpha14 chromosome, complete genome

NCBI: NC_013016

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from healthy carriers during a carriage study performed in 1999/2000 in Bavaria, Germany. This organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

#StartEndLengthIsland TextGRV_RVDPSNeighboursClusterSub ClusterBLASTNKey Word ConfirmationOther DB ConfirmationDownload Island
144188*6967425487Island text2.4706538.697728.1029Neighbours24BLASTN44188.gbk
2354000*38204428045Island text1.7042735.417750.4964Neighbours35BLASTN354000.gbk
341960444166822065Island text2.4728839.121229.2573Neighbours24BLASTN+419604.gbk
4500789*52384323055Island text1.4802831.261429.2629Neighbours35BLASTN+IslandViewer 500789.gbk
5571255*59527524021Island text1.6995634.039323.3206Neighbours35BLASTNIslandViewer 571255.gbk
6633313*65229518983Island text1.8909733.778631.9862Neighbours35BLASTN+633313.gbk
7656000*67948423485Island text1.569232.427443.3325Neighbours35BLASTN656000.gbk
81257942*128009922158Island text1.5961230.1822.0429Neighbours24BLASTN1257942.gbk
91289975*131436424390Island text1.5420928.407729.2606Neighbours24BLASTN+1289975.gbk
101441424*146623224809Island text1.7692933.381820.2821Neighbours24BLASTN+IslandViewer 1441424.gbk
111801000*182570224703Island text1.7259533.956931.5695Neighbours24BLASTN+1801000.gbk
122014368*204109926732Island text1.4905636.168541.619Neighbours320BLASTN+2014368.gbk
132041890*206781525926Island text1.9270433.661221.7657Neighbours35BLASTN2041890.gbk