Pre_GI Gene

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Host: NC_013016 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_013016:1441424 Neisseria meningitidis alpha14 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from healthy carriers during a carriage study performed in 1999/2000 in Bavaria, Germany. This organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
144142414431961773DNA primaseQuickGO ontologyBLASTP
144338314453111929RNA polymerase sigma factor RpoDQuickGO ontologyBLASTP
144575314484642712putative type III restriction enzymeQuickGO ontologyBLASTP
144969114513791689putative type III DNA modification methylaseQuickGO ontologyBLASTP
145139914531381740abortive infection phage resistance proteinQuickGO ontologyBLASTP
145313814559362799putative DEADDEAH box helicaseQuickGO ontologyBLASTP
145643314580671635CTP synthetaseQuickGO ontologyBLASTP
145817914598491671long-chain-fatty-acid--CoA ligaseQuickGO ontologyBLASTP
145992014610231104tRNA-specific 2-thiouridylase MnmAQuickGO ontologyBLASTP
14611491461622474hypothetical proteinBLASTP
14619151462298384Diacylglycerol kinaseQuickGO ontologyBLASTP
14626101463566957glutathione synthetaseQuickGO ontologyBLASTP
146365914653801722glutaminyl-tRNA synthetaseQuickGO ontologyBLASTP
14654591466232774DeoR family transcriptional regulatorQuickGO ontologyBLASTP