Pre_GI Gene

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Host: NC_013016 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_013016:354000 Neisseria meningitidis alpha14 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from healthy carriers during a carriage study performed in 1999/2000 in Bavaria, Germany. This organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
354263354790528lipoprotein signal peptidaseQuickGO ontologyBLASTP
3548193557879694-hydroxy-3-methylbut-2-enyl diphosphate reductaseQuickGO ontologyBLASTP
355875356534660hydrolaseQuickGO ontologyBLASTP
3566943588502157outer membrane ferric siderophore receptorQuickGO ontologyBLASTP
358920359852933putative esteraseQuickGO ontologyBLASTP
360247360582336putative initiator RepB proteinQuickGO ontologyBLASTP
360938361429492hypothetical proteinBLASTP
362417362776360putative cupin family proteinQuickGO ontologyBLASTP
363006363341336hypothetical proteinBLASTP
363521363940420hypothetical proteinBLASTP
363933364268336hypothetical proteinBLASTP
364596364808213hypothetical proteinBLASTP
364832365167336hypothetical proteinBLASTP
365203365808606putative bacteriocin processing proteaseQuickGO ontologyBLASTP
367195367545351hypothetical proteinBLASTP
368248368556309hypothetical proteinBLASTP
368567369481915putative DNA-repair proteinQuickGO ontologyBLASTP
3695473727953249putative CRISPR-associated proteinQuickGO ontologyBLASTP
3730733765073435DNA polymerase III subunit alphaQuickGO ontologyBLASTP
37674837684699hypothetical protein
377039377272234putative RNA-binding proteinQuickGO ontologyBLASTP
377250377453204hypothetical protein
377898378734837putative metal-dependent phosphoesteraseQuickGO ontologyBLASTP
3787863801441359valine--pyruvate transaminaseQuickGO ontologyBLASTP
3801343820441911pilin glycosylation proteinQuickGO ontologyBLASTP