Pre_GI Gene

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Host: NC_013016 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_013016:44188 Neisseria meningitidis alpha14 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from healthy carriers during a carriage study performed in 1999/2000 in Bavaria, Germany. This organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
44188456721485hypothetical proteinBLASTP
4574745962216hypothetical proteinBLASTP
4595546197243hypothetical proteinBLASTP
46245475881344argininosuccinate synthaseQuickGO ontologyBLASTP
4805248852801putative molybdopterin-binding proteinQuickGO ontologyBLASTP
4889249878987putative ClpP class peptidaseQuickGO ontologyBLASTP
5138251738357hypothetical proteinBLASTP
5174351937195putative MafB alternative C-terminusQuickGO ontologyBLASTP
5229252651360hypothetical proteinBLASTP
5264852866219hypothetical proteinBLASTP
53059545821524putative adhesin MafBQuickGO ontologyBLASTP
5470254836135hypothetical proteinBLASTP
5507655486411hypothetical proteinBLASTP
5636956725357hypothetical proteinBLASTP
5689157265375hypothetical proteinBLASTP
5726258158897putative adhesin MafBQuickGO ontologyBLASTP
5826058778519putative adhesin MafB truncatedQuickGO ontologyBLASTP
5881859780963putative adhesin MafAQuickGO ontologyBLASTP
5996460683720uridylate kinaseQuickGO ontologyBLASTP
6090061754855elongation factor TsQuickGO ontologyBLASTP
618846261272930S ribosomal protein S2QuickGO ontologyBLASTP
6278963022234hypothetical proteinBLASTP
6310063681582putative formyltetrahydrofolate cyclo-ligaseQuickGO ontologyBLASTP
6374264332591hypothetical proteinBLASTP
64869663351467malatequinone oxidoreductaseQuickGO ontologyBLASTP
6652367083561hypothetical proteinBLASTP
6713567434300hypothetical proteinBLASTP
6758968368780Methionine aminopeptidaseQuickGO ontologyBLASTP
6840869058651hypothetical proteinBLASTP
6906669674609putative outer membrane or periplasmic OsmY-type proteinQuickGO ontologyBLASTP