Pre_GI Gene

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Host: NC_013016 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_013016:1257942 Neisseria meningitidis alpha14 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from healthy carriers during a carriage study performed in 1999/2000 in Bavaria, Germany. This organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
125794212593301389putative ATP-dependent RNA helicaseQuickGO ontologyBLASTP
12599751260529555hypothetical proteinBLASTP
12606141261114501hypothetical proteinBLASTP
126151812627111194bifunctional N-succinyldiaminopimelate-aminotransferaseacetylornithine transaminase proteinQuickGO ontologyBLASTP
126277612640201245ATP-dependent protease ATP-binding subunit ClpXQuickGO ontologyBLASTP
12642101264581372ribosome-binding factor AQuickGO ontologyBLASTP
12645711265116546hypothetical proteinBLASTP
12651741266094921tRNA pseudouridine synthase BQuickGO ontologyBLASTP
126843012712102781putative type III restriction endonucleaseQuickGO ontologyBLASTP
127134612725871242L-lactate dehydrogenaseQuickGO ontologyBLASTP
12728681273314447putative transcription factorQuickGO ontologyBLASTP
127334312745571215cysteine desulfuraseQuickGO ontologyBLASTP
12745421274751210hypothetical proteinBLASTP
12748171275203387scaffold proteinQuickGO ontologyBLASTP
12752901275610321HesBYadRYfhF family proteinQuickGO ontologyBLASTP
12758731276373501chaperone proteinQuickGO ontologyBLASTP
127647112792212751DNA gyrase subunit AQuickGO ontologyBLASTP