Pre_GI Gene

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Host: NC_013016 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_013016:1289975 Neisseria meningitidis alpha14 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from healthy carriers during a carriage study performed in 1999/2000 in Bavaria, Germany. This organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
12899751290613639keto-hydroxyglutarate-aldolaseketo-deoxy- phosphogluconate aldolaseQuickGO ontologyBLASTP
129207312931131041AG-specific adenine glycosylaseQuickGO ontologyBLASTP
12931281293295168hypothetical proteinBLASTP
12935301294090561superoxide dismutaseQuickGO ontologyBLASTP
129565912978872229putative cytolysin secretion ABC transporterQuickGO ontologyBLASTP
12995761300010435hypothetical proteinBLASTP
13000511300242192FrpAC-related protein truncatedQuickGO ontologyBLASTP
13002771301005729hypothetical proteinBLASTP
130099213052604269FrpAC-like proteinQuickGO ontologyBLASTP
130560213082052604aminopeptidase NQuickGO ontologyBLASTP
13083411309135795hypothetical proteinBLASTP
13092511309385135hypothetical proteinBLASTP
13098851310766882lipid A biosynthesis lauroyl acyltransferaseQuickGO ontologyBLASTP
13108051311341537Holliday junction resolvaseQuickGO ontologyBLASTP
13113441311583240DNA-binding protein FisQuickGO ontologyBLASTP
131161313127371125putative tRNA-dihydrouridine synthaseQuickGO ontologyBLASTP
131299113143641374putative ATP-dependent RNA helicaseQuickGO ontologyBLASTP