Pre_GI Gene

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Host: NC_013016 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_013016:419604 Neisseria meningitidis alpha14 chromosome, complete genome

Host Lineage: Neisseria meningitidis; Neisseria; Neisseriaceae; Neisseriales; Proteobacteria; Bacteria

General Information: Isolated from healthy carriers during a carriage study performed in 1999/2000 in Bavaria, Germany. This organism causes septicemia and is the leading cause of life-threatening meningitis (inflammation of the meninges, the membrane surrounding the brain and spinal cord) in children. This organism typically residies in the nasopharynx cavity but can invade the respiratory epthelial barrier, cross into the bloodstream and the blood brain barrier, and cause inflammation of the meninges. Pathogenicity factors include the surface proteins (porins and opacity proteins), and the type IV pilus (which is also found in Neisseria gonorrhoeae). This organism, like Neisseria gonorrhoeae, is naturally competent, and protein complexes at the cell surface recognize the uptake signal sequence in extracellular DNA, an 8mer that is found at high frequency in Neisseria chromosomal DNA.

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
419604420047444preprotein translocase subunit SecBQuickGO ontologyBLASTP
4201334221752043ATP-dependent DNA helicase RecGQuickGO ontologyBLASTP
4232874243301044N-acetyl-gamma-glutamyl-phosphate reductaseQuickGO ontologyBLASTP
424327424608282hypothetical proteinBLASTP
424790425599810hypothetical proteinBLASTP
425608425835228hypothetical proteinBLASTP
425774426181408putative secreted proteinQuickGO ontologyBLASTP
427334427636303hypothetical proteinBLASTP
427651427821171hypothetical proteinBLASTP
4282204299621743hemolysin activation proteinQuickGO ontologyBLASTP
4300714360225952hemagglutininhemolysin-like proteinQuickGO ontologyBLASTP
436025436960936hypothetical proteinBLASTP
437349437699351hypothetical proteinBLASTP
438266438724459hypothetical proteinBLASTP
438936439217282ABC transporterQuickGO ontologyBLASTP
4392384404941257bifunctional ribonuclease BNhypothetical proteinQuickGO ontologyBLASTP
441009441668660putative aluminum resistance proteinQuickGO ontologyBLASTP