Pre_GI Island

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n1_4mer:GRV/n1_4mer:RV = (Global Relative Variance of OU patterns) / (Local Relative Variance of OU patterns)

n0_4mer:D = Distance between local and global OU patterns

n0_4mer:PS = Distance between 2 strands of same DNA molecule

Selected loci indicated by large D, increased GRV associated with decreased RV and moderate increase in PS

NC_010673: Borrelia hermsii DAH, complete genome

NCBI: NC_010673

Host Lineage: Borrelia hermsii; Borrelia; Spirochaetaceae; Spirochaetales; Spirochaetes; Bacteria

General Information: This strain was isolated from a case of relapsing fever in western Washington, USA. Borrelia hermsii is the causative agent of tick-borne relapsing fever in the western United States and Canada. Borrelia then multiplies rapidly, causing a generalized infection throughout the tick. While feeding, the tick passes the organism into a mammalian host through its infectious saliva. Relapsing fever is characterized by a period of chills, fever, headache, and malaise, an asymptomatic period, followed by another episode of symptoms. This cycle of relapsing is due to changes in the surface proteins of Borrelia, which allow it to avoid detection and removal by the host immune system. This antigenic variation is the result of homologous recombination of silent proteins into an expressed locus, causing partial or complete replacement of one serotype with another. These plasmids carry genes involved in antigenic variation and pathogenicity.

Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

#StartEndLengthIsland TextGRV_RVDPSNeighboursClusterSub ClusterBLASTNKey Word ConfirmationOther DB ConfirmationDownload Island
182586*10109918514Island text1.9410318.348735.9605Neighbours21BLASTN82586.gbk
2113133*13311219980Island text1.8417218.564634.4987Neighbours21BLASTN113133.gbk
3205500*22759922100Island text5.539319.543437.5454Neighbours21BLASTN+205500.gbk
429167931681725139Island text1.7862918.4333.0258Neighbours21BLASTN291679.gbk
5388442*40681618375Island text1.8328418.75332.6349Neighbours21BLASTN+388442.gbk
6479552*50738827837Island text1.9863918.940236.6153Neighbours21BLASTN+479552.gbk
7578474*60233723864Island text1.700117.844134.2916Neighbours21BLASTN+578474.gbk
8703816*75732453509Island text1.8911319.60937.0587Neighbours21BLASTN+703816.gbk
9908940*93249923560Island text2.581319.015536.0397Neighbours21BLASTN908940.gbk