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Query: NC_017168:561402:580904 Yersinia pestis A1122 chromosome, complete genome

Start: 580904, End: 581281, Length: 378

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009381:3558018:357752035775203577897378Yersinia pestis Pestoides F chromosome, complete genomeApaG protein8e-68254
NC_010159:770172:789667789667790044378Yersinia pestis Angola, complete genomeapaG protein8e-68254
NC_005810:4183297:420279942027994203176378Yersinia pestis biovar Microtus str. 91001, complete genomeApaG8e-68254
NC_004088:4073698:409565240956524096029378Yersinia pestis KIM, complete genomehypothetical protein8e-68254
NC_009708:3862044:388401738840173884394378Yersinia pseudotuberculosis IP 31758 chromosome, complete genomeApaG protein4e-67252
NC_010465:3919572:393909339390933939470378Yersinia pseudotuberculosis YPIII, complete genomeApaG domain protein4e-67252
NC_016632:170000:213241213241213618378Serratia symbiotica str. 'Cinara cedri' chromosome, completeCo2+ and Mg2+ efflux protein8e-54208
NC_009434:796878:828360828360828743384Pseudomonas stutzeri A1501, complete genomeApaG1e-29128
NC_013851:2441407:246032824603282460699372Allochromatium vinosum DSM 180 chromosome, complete genomeApaG domain protein2e-29127
NC_007614:2675302:269834726983472698730384Nitrosospira multiformis ATCC 25196 chromosome 1, completeProtein of unknown function DUF5252e-26117
NC_008343:88184:972259722597734510Granulibacter bethesdensis CGDNIH1, complete genomeapaG protein1e-24111
NC_015711:237526:258052258052258438387Myxococcus fulvus HW-1 chromosome, complete genomeCO2+/MG2+ efflux protein ApaG4e-23106