Pre_GI Gene

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Host: NC_009381 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_009381:3558018 Yersinia pestis Pestoides F chromosome, complete genome

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Atypical strain isolated from the former Soviet Union, USSR. This strain lacks a plasminogen activator and is virulent by the aerosol route. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
355801835606062589Clp ATPaseQuickGO ontologyBLASTP
35606243561607984hypothetical proteinBLASTP
356160035634441845hypothetical proteinBLASTP
35634773563920444hypothetical proteinBLASTP
35639943564512519hypothetical proteinBLASTP
356467535661861512hypothetical proteinBLASTP
35661863566746561hypothetical proteinBLASTP
35667573567755999hypothetical proteinBLASTP
35681813568843663hypothetical proteinBLASTP
35700663570686621ribosomal large subunit pseudouridine synthase AQuickGO ontologyBLASTP
35709843571817834Dna-J like membrane chaperone proteinQuickGO ontologyBLASTP
357196635743442379organic solvent tolerance proteinQuickGO ontologyBLASTP
357441235757161305peptidyl-prolyl cis-trans isomerase SurAQuickGO ontologyBLASTP
3575691357669510054-hydroxythreonine-4-phosphate dehydrogenaseQuickGO ontologyBLASTP
35766883577506819dimethyladenosine transferaseQuickGO ontologyBLASTP
35775203577897378ApaG proteinQuickGO ontologyBLASTP