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Query: NC_014039:499233:511692 Propionibacterium acnes SK137 chromosome, complete genome

Start: 511692, End: 511847, Length: 156

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016516:463460:475925475925476080156Propionibacterium acnes TypeIA2 P.acn33 chromosome, completeS-ribosylhomocysteinase4e-23106
NC_016511:472666:485128485128485283156Propionibacterium acnes TypeIA2 P.acn31 chromosome, completeS-ribosylhomocysteinase4e-23106
NC_006085:481231:495789495789496271483Propionibacterium acnes KPA171202, complete genomeS-ribosylhomocysteinase8e-2199
NC_014039:499233:513786513786514283498Propionibacterium acnes SK137 chromosome, complete genomeS-ribosylhomocysteinase LuxS8e-2095.5
NC_016516:463460:478019478019478483465Propionibacterium acnes TypeIA2 P.acn33 chromosome, completeS-ribosylhomocysteinase1e-1995.1
NC_016511:472666:487223487223487687465Propionibacterium acnes TypeIA2 P.acn31 chromosome, completeS-ribosylhomocysteinase1e-1995.1
NC_014246:676570:700232700232700699468Mobiluncus curtisii ATCC 43063 chromosome, complete genomeS-ribosylhomocysteinase6e-1166.2
NC_012590:284793:302269302269302745477Corynebacterium aurimucosum ATCC 700975, complete genomeputative S-ribosylhomocysteinase3e-0960.5