Pre_GI Gene

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Host: NC_016511 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016511:472666 Propionibacterium acnes TypeIA2 P.acn31 chromosome, complete

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
472055472669615cobIalamin adenolsyltransferasecobinamide ATP-dependent adenolsyltransferaseQuickGO ontologyBLASTP
4726664750922427cobyrinic acid ac-diamide synthaseQuickGO ontologyBLASTP
475102475878777uroporphyrinogen-III C-methyltransferaseQuickGO ontologyBLASTP
475898476650753precorrin-6x reductase CbiJCobKQuickGO ontologyBLASTP
4768744785441671nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferaseQuickGO ontologyBLASTP
478541479380840cobalamin-5-phosphate synthase CobSQuickGO ontologyBLASTP
479341480141801metal binding proteinQuickGO ontologyBLASTP
48019848027376tRNA-ThrQuickGO ontologyBLASTP
4803634820001638hypothetical proteinBLASTP
482172482303132hypothetical proteinBLASTP
4826574842461590PTS system ascorbate-specific transporter subunit IICQuickGO ontologyBLASTP
484296485060765phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2QuickGO ontologyBLASTP
485128485283156S-ribosylhomocysteinaseQuickGO ontologyBLASTP
485360485536177hypothetical proteinBLASTP
486662487072411hypothetical proteinBLASTP
487223487687465S-ribosylhomocysteinaseQuickGO ontologyBLASTP
4877434889241182mannose-6-phosphate isomeraseQuickGO ontologyBLASTP
488968489252285hypothetical proteinBLASTP
4895864912201635chaperonin GroLQuickGO ontologyBLASTP
4913554924311077transaldolaseQuickGO ontologyBLASTP
492533493276744UbiC transcription regulator-associated proteinQuickGO ontologyBLASTP
493491494480990carbohydrate kinaseQuickGO ontologyBLASTP
494477495364888hypothetical proteinBLASTP
495361496233873Myo-inositol catabolism proteinQuickGO ontologyBLASTP