Pre_GI Gene

Some Help

Host: NC_016516 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016516:463460 Propionibacterium acnes TypeIA2 P.acn33 chromosome, complete

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline. Some other forms of therapy include chemicals that enhance skin removal or slow the production of sebum.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
462852463466615cobIalamin adenolsyltransferasecobinamide ATP-dependent adenolsyltransferaseQuickGO ontologyBLASTP
4634604658892430cobyrinic acid ac-diamide synthaseQuickGO ontologyBLASTP
465899466675777uroporphyrinogen-III C-methyltransferaseQuickGO ontologyBLASTP
466695467447753precorrin-6x reductase CbiJCobKQuickGO ontologyBLASTP
4676744693411668nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferaseQuickGO ontologyBLASTP
469338470177840cobalamin-5-phosphate synthase CobSQuickGO ontologyBLASTP
470138470938801metal binding proteinQuickGO ontologyBLASTP
47099547107076tRNA-ThrQuickGO ontologyBLASTP
4711604727971638hypothetical proteinBLASTP
472969473100132hypothetical proteinBLASTP
4734544750431590PTS system ascorbate-specific transporter subunit IICQuickGO ontologyBLASTP
475093475857765phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2QuickGO ontologyBLASTP
475925476080156S-ribosylhomocysteinaseQuickGO ontologyBLASTP
476157476333177hypothetical proteinBLASTP
477389477868480hypothetical proteinBLASTP
478019478483465S-ribosylhomocysteinaseQuickGO ontologyBLASTP
4785394797201182mannose-6-phosphate isomeraseQuickGO ontologyBLASTP
479764480048285hypothetical proteinBLASTP
4803824820161635chaperonin GroLQuickGO ontologyBLASTP
4821514832271077transaldolaseQuickGO ontologyBLASTP
483329484072744UbiC transcription regulator-associated proteinQuickGO ontologyBLASTP
484287485276990carbohydrate kinaseQuickGO ontologyBLASTP
485273486160888hypothetical proteinBLASTP
486157487029873Myo-inositol catabolism proteinQuickGO ontologyBLASTP