Pre_GI Gene

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Host: NC_014039 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_014039:499233 Propionibacterium acnes SK137 chromosome, complete genome

Host Lineage: Propionibacterium acnes; Propionibacterium; Propionibacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: This bacterium is the most common gram-positive, non-spore forming, anaerobic rod encountered in clinical specimens. The causative agent of acne, it typically grows as an obligate anaerobe. Some strains are aerotolerant, but still show better growth as an anaerobe. It has the ability to produce propionic acid, as its name suggests. It also has the ability to produce catalase along with indole, nitrate, or both indole and nitrate. Propionibacterium resembles Corynebacterium in morphology and arrangement, but is non-toxigenic. It is a common resident of the pilosebaceous (hair follicle) glands of the human skin. The bacteria release lipases to digest a surplus of the skin oil, sebum, that has been produced. The combination of digestive products (fatty acids) and bacterial antigens stimulates an intense local inflammation that bursts the hair follicle. Since acne is caused in part from an infection, it can be suppressed with topical and oral antibiotics such as clindamycin, erythromycin, or tetracycline.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
4992335016562424cobyrinic acid ac-diamide synthaseQuickGO ontologyBLASTP
501666502442777uroporphyrinogen-III C-methyltransferaseQuickGO ontologyBLASTP
502462503214753precorrin-6x reductase CbiJCobKQuickGO ontologyBLASTP
5034415051081668nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferaseQuickGO ontologyBLASTP
505099505944846cobalamin-5-phosphate synthaseQuickGO ontologyBLASTP
505941506705765hypothetical proteinBLASTP
50676250683776tRNA-ThrQuickGO ontologyBLASTP
5069275085641638hypothetical proteinBLASTP
508615508767153hypothetical protein
508736508867132hypothetical proteinBLASTP
5092215108101590hypothetical proteinBLASTP
510860511624765phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2QuickGO ontologyBLASTP
511692511847156hypothetical proteinBLASTP
511924512100177hypothetical proteinBLASTP
512187512345159hypothetical protein
513189513635447hypothetical proteinBLASTP
513786514283498S-ribosylhomocysteinase LuxSQuickGO ontologyBLASTP
5143065154871182mannose-6-phosphate isomerase class IQuickGO ontologyBLASTP
515531515815285hypothetical proteinBLASTP
5161495177831635chaperonin GroLQuickGO ontologyBLASTP
5179185189941077transaldolaseQuickGO ontologyBLASTP
519096519839744UbiC transcription regulator-associatedQuickGO ontologyBLASTP
520054521043990kinase PfkB familyQuickGO ontologyBLASTP
521040521927888deoxyribose-phosphate aldolaseQuickGO ontologyBLASTP
521924522796873Myo-inositol catabolism proteinQuickGO ontologyBLASTP