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Query: NC_012207:3421144:3432450 Mycobacterium bovis BCG str. Tokyo 172, complete genome

Start: 3432450, End: 3432920, Length: 471

Host Lineage: Mycobacterium bovis; Mycobacterium; Mycobacteriaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Used for the production of BCG vaccine in Japan. Causative agent of classic bovine tuberculosis. This bacterium is the causative agent of classic bovine tuberculosis, but it can also cause the disease in humans, especially if contaminated milk is consumed without prior pasteurization. The Mycobacterium bovis complex is a diverse group of species, serovars and morphotypes that cause tuberculosis-like diseases in animals and humans. Pasteurization of milk is a major preventitive factor in transmission of bovine tuberculosis to humans. However, spreading the disease through milk and dairy products is still a concern in underdeveloped countries where pasteurization is not practiced. The pathology in cows is similar to the pathology of Mycobacterium tuberculosis in humans, with pulmonary TB leading to chronic debilitation, coughing, and further systemic spread to other organs. In addition, 1 to 2% of infected cows develop mycobacterial mastitis that results in shedding of the bacteria into the milk.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_016804:3407859:341916534191653419635471Mycobacterium bovis BCG str. Mexico chromosome, complete genomehypothetical protein3e-73273
NC_002945:3429315:344186134418613442331471Mycobacterium bovis AF2122/97, complete genomehypothetical protein3e-73273
NC_008769:3427254:343980034398003440270471Mycobacterium bovis BCG str. Pasteur 1173P2, complete genomehypothetical protein3e-73273
NC_009525:3484924:350024535002453500715471Mycobacterium tuberculosis H37Ra, complete genomehypothetical protein3e-73273
NC_009565:3485772:350121235012123501682471Mycobacterium tuberculosis F11, complete genomehypothetical protein3e-73273
NC_002755:3465582:348388634838863484356471Mycobacterium tuberculosis CDC1551, complete genomehypothetical protein3e-73273
NC_000962:3474000:348808934880893488559471Mycobacterium tuberculosis H37Rv, complete genomehypothetical protein3e-73273
NC_017026:3466809:348236134823613482615255Mycobacterium tuberculosis RGTB327 chromosome, complete genomehypothetical protein7e-23106