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Query: NC_007613:1038000:1039505 Shigella boydii Sb227, complete genome

Start: 1039505, End: 1039708, Length: 204

Host Lineage: Shigella boydii; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This strain is an isolate from an epidemic that took place in China in the 1950s. Causes dysentery. This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. Shigella boydii is uncommon except in India, where it was first isolated. Progression to clinical dysentery occurs in most patients infected with this organism.

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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_011601:1269500:1288980128898012908301851Escherichia coli O127:H6 str. E2348/69 chromosome, complete genomehypothetical protein2e-29127
NC_013008:3525428:3543237354323735450901854Escherichia coli O157:H7 str. TW14359 chromosome, complete genomehypothetical protein8e-28122
NC_011353:3573641:3588360358836035902131854Escherichia coli O157:H7 str. EC4115 chromosome, complete genomehypothetical protein8e-28122
NC_002695:3468873:3484252348425234861051854Escherichia coli O157:H7 str. Sakai, complete genomehypothetical protein8e-28122
NC_011748:1408280:1426724142672414285801857Escherichia coli 55989, complete genomehypothetical protein4e-27119
CU928145:1408280:1426724142672414285801857Escherichia coli 55989 chromosome, complete genomeconserved hypothetical protein4e-27119
NC_002655:3538656:3552256355225635534281173Escherichia coli O157:H7 EDL933, complete genomeunknown protein encoded by prophage CP-933Y6e-27119
NC_010658:1933605:1953573195357319555341962Shigella boydii CDC 3083-94, complete genome2e-23107
NC_002695:1929215:1941996194199619438491854Escherichia coli O157:H7 str. Sakai, complete genomehypothetical protein4e-22103
NC_007384:1320287:133529913352991335487189Shigella sonnei Ss046, complete genomehypothetical protein3e-22103
NC_002655:2142587:2143317214331721451671851Escherichia coli O157:H7 EDL933, complete genomeunknown protein encoded within prophage CP-933R8e-22102
NC_013361:1754346:1756560175656017584131854Escherichia coli O26:H11 str. 11368 chromosome, complete genomehypothetical protein3e-21100
NC_016822:1304398:131891713189171319090174Shigella sonnei 53G, complete genomehypothetical protein4e-1993.6
NC_013008:2910567:2916512291651229184581947Escherichia coli O157:H7 str. TW14359 chromosome, complete genomehypothetical protein3e-1373.9
NC_011353:2957962:2961641296164129635871947Escherichia coli O157:H7 str. EC4115 chromosome, complete genomehypothetical protein3e-1373.9
NC_013364:1596278:1617129161712916190751947Escherichia coli O111:H- str. 11128, complete genomehypothetical protein3e-1373.9