Pre_GI Gene

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Host: NC_016822 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_016822:1304398 Shigella sonnei 53G, complete genome

Host Lineage: Shigella sonnei; Shigella; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: This genus is named for the Japanese scientist (Shiga) who first discovered these organisms in the 1890s. They are closely related to the Escherichia group, and may be considered the same species. These organisms are human-specific pathogens that are transmitted via contaminated food and water and are the leading causes of endemic bacillary dysentery, causing over 160 million cases of infection and 1 million deaths yearly worldwide. The bacteria infect the epithelial lining of the colon, causing acute inflammation by entering the host cell cytoplasm and spreading intercellularly. are extremely virulent organisms that can cause an active infection after a very low exposure. Both the type III secretion system, which delivers effector molecules into the host cell, and some of the translocated effectors such as the invasion plasmid antigens (Ipas), are encoded on the plasmid. The bacterium produces a surface protein that localizes to one pole of the cell (IcsA) which binds to and promotes actin polymerization, resulting in movement of the bacterium through the cell cytoplasm, and eventually to neighboring cells, which results in inflammatory destruction of the mucosal lining. This organism is the leading cause of dysentery in industrialized countries. The disease is usually less severe than other types of Shigella, causing mild diarrhea and dehydration.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
130439813054981101NapCNirT cytochrome c domain proteinQuickGO ontologyBLASTP
130552313079522430molybdopterin guanine dinucleotide-containing SN-oxide reductaseQuickGO ontologyBLASTP
13081171309088972tRNA mo5U34 methyltransferaseQuickGO ontologyBLASTP
13090851309828744tRNA cmo5U34 methyltransferaseQuickGO ontologyBLASTP
13098691310264396hypothetical proteinBLASTP
13103171310664348hypothetical proteinBLASTP
13112511311802552resolvaseQuickGO ontologyBLASTP
13121711312833663DNA methylaseQuickGO ontologyBLASTP
13131971313586390hypothetical proteinBLASTP
13137361314083348hypothetical proteinBLASTP
13140831314373291hypothetical protein
13143701314555186hypothetical protein
13146941314984291hypothetical protein
13149841315403420hypothetical protein
13155711315894324hypothetical proteinBLASTP
13160321316205174hypothetical protein
13163241316935612hypothetical proteinBLASTP
13169871317289303IS600 orf1QuickGO ontologyBLASTP
13174301318053624integraseQuickGO ontologyBLASTP
13180641318567504IS1 ORF2QuickGO ontologyBLASTP
13184861318761276IS1 repressor protein InsAQuickGO ontologyBLASTP
13189171319090174hypothetical proteinBLASTP
13193631319686324anti-adapter protein IraMQuickGO ontologyBLASTP
1319967132005387hypothetical protein
13201341320412279hypothetical proteinBLASTP
13209531321807855antitermination protein QQuickGO ontologyBLASTP
13218041322178375crossover junction endodeoxyribonucleaseQuickGO ontologyBLASTP
13221781322435258bacteriophage proteinQuickGO ontologyBLASTP
13227701323567798IS21 ORF2QuickGO ontologyBLASTP
132356713247391173integrase for IS21 orfAQuickGO ontologyBLASTP
13248451325030186IS2 repressor TnpAQuickGO ontologyBLASTP
13249881325893906IS2 transposase TnpBQuickGO ontologyBLASTP
13260101326312303IS600 ORF1QuickGO ontologyBLASTP
13264531327166714IS600 ORF2QuickGO ontologyBLASTP
13271941328147954phage tail fiber proteinQuickGO ontologyBLASTP
13280981328721624tail component of prophageQuickGO ontologyBLASTP
13287211328900180hypothetical protein