Pre_GI: BLASTP Hits

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Query: NC_005810:4381182:4399725 Yersinia pestis biovar Microtus str. 91001, complete genome

Start: 4399725, End: 4400135, Length: 411

Host Lineage: Yersinia pestis; Yersinia; Enterobacteriaceae; Enterobacteriales; Proteobacteria; Bacteria

General Information: Causative agent of plague. Specific virulence factors are encoded within pathogenicity islands (PAIs) that are required for the invasive phenotype associated with Yersinia infections. One key virulence plasmid contained by the three human-specific pathogens is pCD1/pYv, which encodes a type III secretion system for the delivery of virulence proteins that contribute to internalization into the host cell. It is the causative agent of plague (bubonic and pulmonary) a devastating disease which has killed millions worldwide. The organism can be transmitted from rats to humans through the bite of an infected flea or from human-to-human through the air during widespread infection. Yersinia pestis is an extremely pathogenic organism that requires very few numbers in order to cause disease, and is often lethal if left untreated. The organism is enteroinvasive, and can survive and propagate in macrophages prior to spreading systemically throughout the host. Yersinia pestis consists of three biotypes or serovars, Antiqua, Mediavalis, and Orientalis, that are associated with three major pandemics throughout human history. pMT1 encodes a protein, murine toxin, that aids rat-to-human transmission by enhancing survival of the organism in the flea midgut. Yersinia pestis also contains a PAI on the chromosome that is similar to the SPI-2 PAI from Salmonella that allows intracellular survival in the organism.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_004088:179775:197977197977198387411Yersinia pestis KIM, complete genomehypothetical protein8e-68254
NC_017265:4171500:418893341889334189334402Yersinia pestis biovar Medievalis str. Harbin 35 chromosome,putative phage-like protein4e-66249
NC_017160:3986844:400505440050544005455402Yersinia pestis D182038 chromosome, complete genomeputative phage-like protein4e-66249
NC_008149:3966586:398479739847973985198402Yersinia pestis Nepal516, complete genomehypothetical protein4e-66249
NC_010159:1208699:122887812288781229279402Yersinia pestis Angola, complete genomepeptidase M15 family4e-66249
NC_010634:4150763:416925341692534169654402Yersinia pseudotuberculosis PB1/+, complete genomeputative phage-related protein3e-65246
NC_006155:4210606:422911442291144229515402Yersinia pseudotuberculosis IP 32953, complete genomeputative phage-related protein3e-65246
NC_015224:4028150:404464840446484045049402Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,Peptidase M15 family2e-53207
NC_012962:3933715:393483239348323935230399Photorhabdus asymbiotica, complete genomePhage-related protein precursor9e-42168
NC_015224:2095816:209871320987132099108396Yersinia enterocolitica subsp. palearctica 105.5R(r) chromosome,putative phagelysin2e-32137
NC_014640:4293430:430419143041914304601411Achromobacter xylosoxidans A8 chromosome, complete genomehypothetical protein2e-31134
NC_016902:2580774:258568925856892586066378Escherichia coli KO11FL chromosome, complete genomephage capsid scaffolding protein5e-31132
CP002516:2580774:258568925856892586066378Escherichia coli KO11, complete genomephage capsid scaffolding protein5e-31132
NC_014922:825396:850013850013850417405Haemophilus influenzae F3047 chromosome, complete genomehypothetical protein2e-27120
NC_007645:4677965:468376546837654684148384Hahella chejuensis KCTC 2396, complete genomeprobable phage protein2e-25114
NC_013892:3803278:382600038260003826398399Xenorhabdus bovienii SS-2004 chromosome, complete genomehypothetical protein8e-25112
NC_012751:1538500:154336715433671543852486Candidatus Hamiltonella defensa 5AT (Acyrthosiphon pisum), completephage endolysin2e-22104
NC_013766:679906:713248713248714093846Listeria monocytogenes 08-5578 chromosome, complete genomeL-alanoyl-D-glutamate peptidase9e-1165.5
NC_003210:2362306:236475423647542365599846Listeria monocytogenes EGD-e, complete genomeL-alanoyl-D-glutamate peptidase3e-0960.8
NC_010943:3069082:308965130896513090445795Stenotrophomonas maltophilia K279a, complete genomeputative peptidase6e-0649.7