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Query: NC_004668:3184319 Enterococcus faecalis V583, complete genome

Start: 3184319, End: 3211999, Length: 27681

Host Lineage: Enterococcus faecalis; Enterococcus; Enterococcaceae; Lactobacillales; Firmicutes; Bacteria

General Information: This strain is one of the first vancomycin-resistant strains isolated. This isolate came from a blood culture derived from a chronically-infected patient in 1987 from Barnes Hospital in St. Louis, Missouri, USA. This strain was found to lack the cytolysin gene and a surface adhesin, Esp, that contributes to urinary tract infections. Mobile genetic elements make up one quarter of the genome. This genera consists of organisms typically found in the intestines of mammals, although through fecal contamination they can appear in sewage, soil, and water. They cause a number of infections that are becoming increasingly a problem due to the number of antibiotic resistance mechanisms these organisms have picked up. Both Enterococcus faecalis and Enterococcus faecium cause similar diseases in humans, and are mainly distinguished by their metabolic capabilities. This opportunistic pathogen can cause urinary tract infections, bacteremia (bacteria in the blood), and infective endocarditis (inflammation of the membrane surrounding the heart), similar to infections caused by Enterococcus faecium. Hospital-acquired infections from this organism are on the rise due to the emergence of antiobiotic resistance strains. Enterococcus faecalis produces a cytolysin toxin that is encoded on various mobile genetic elements, pathogenicity islands, and conjugative plasmids. The cytolysin aids in pathogenesis, possibly by causing destruction of cells such as erythrocytes, which allows access to new nutrients for the organism.

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Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

Subject IslandStartEndLengthSubject Host DescriptionE-valueBit scoreVisual BLASTNVisual BLASTP
NC_016011:28757472875747290001324267Listeria ivanovii subsp. ivanovii PAM 55, complete genome5e-33151BLASTN svgBLASTP svg
NC_005945:5202176*5202176522486522690Bacillus anthracis str. Sterne, complete genome7e-32147BLASTN svgBLASTP svg
NC_003997:5200805*5200805522349422690Bacillus anthracis str. Ames, complete genome7e-32147BLASTN svgBLASTP svg
NC_015978:1266196*1266196129576529570Lactobacillus sanfranciscensis TMW 1.1304 chromosome, complete3e-31145BLASTN svgBLASTP svg
NC_003210:2879906*2879906290440224497Listeria monocytogenes EGD-e, complete genome3e-28135BLASTN svgBLASTP svg
NC_004722:5381208*5381208540929928092Bacillus cereus ATCC 14579, complete genome7e-26127BLASTN svgBLASTP svg
NC_007576:1854136*1854136187957225437Lactobacillus sakei subsp. sakei 23K, complete genome4e-24121BLASTN svgBLASTP svg
NC_007930:18028118028119859918319Lactobacillus salivarius subsp. salivarius UCC118 plasmid pMP118,4e-24121BLASTN svgBLASTP svg
NC_003923:27946862794686281805223367Staphylococcus aureus subsp. aureus MW2, complete genome5e-1177.8BLASTN svgBLASTP svg
NC_009004:2477220*2477220250009922880Lactococcus lactis subsp. cremoris MG1363, complete genome3e-0971.9BLASTN svgBLASTP svg
NC_004461:74628474628477013223849Staphylococcus epidermidis ATCC 12228, complete genome1e-0869.9BLASTN svgBLASTP svg
NC_002976:63879963879966264823850Staphylococcus epidermidis RP62A, complete genome1e-0869.9BLASTN svgBLASTP svg