Query: NC_004557:749330 Clostridium tetani E88, complete genome
Start: 749330, End: 770099, Length: 20770
Host Lineage: Clostridium tetani; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria
General Information: This strain is a virulent nonsporulating variant of strain Massachusetts used in vaccine production. Causes tetanus. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. Known opportunistic toxin-producing pathogens in animals and humans. Some species are capable of producing organic solvents (acetone, ethanol, etc,), molecular hydrogen and other useful compounds. This organism causes tetanus (lockjaw) in humans. At the tissue level, the bacterium then releases an exotoxin called tetanospasmin that causes certain nervous system irregularities by means of retrograde tramsmission through neurons to the brain. If nervous impulses cannot be checked by normal inhibitory mechanisms, it produces the generalized muscular spasms characteristic of tetanus.
Islands with an asterisk (*) contain ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!
Subject Island | Start | End | Length | Subject Host Description | E-value | Bit score | Visual BLASTN | Visual BLASTP |
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NC_021182:1245692 | 1245692 | 1263704 | 18013 | Clostridium pasteurianum BC1, complete genome | 1e-42 | 182 | BLASTN svg | BLASTP svg |
NC_014328:3482980 | 3482980 | 3510057 | 27078 | Clostridium ljungdahlii ATCC 49587 chromosome, complete genome | 4e-39 | 170 | BLASTN svg | BLASTP svg |
NC_015687:1508664 | 1508664 | 1532155 | 23492 | Clostridium acetobutylicum DSM 1731 chromosome, complete genome | 5e-32 | 147 | BLASTN svg | BLASTP svg |
NC_003030:1510000 | 1510000 | 1545434 | 35435 | Clostridium acetobutylicum ATCC 824, complete genome | 5e-32 | 147 | BLASTN svg | BLASTP svg |
NC_015687:95918* | 95918 | 117387 | 21470 | Clostridium acetobutylicum DSM 1731 chromosome, complete genome | 5e-26 | 127 | BLASTN svg | BLASTP svg |
NC_003030:95918* | 95918 | 117387 | 21470 | Clostridium acetobutylicum ATCC 824, complete genome | 5e-26 | 127 | BLASTN svg | BLASTP svg |
NC_008593:2250871 | 2250871 | 2268934 | 18064 | Clostridium novyi NT, complete genome | 5e-20 | 107 | BLASTN svg | BLASTP svg |
NC_008593:1917118* | 1917118 | 1965286 | 48169 | Clostridium novyi NT, complete genome | 5e-20 | 107 | BLASTN svg | BLASTP svg |
NC_020291:3900046 | 3900046 | 3925362 | 25317 | Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genome | 1e-14 | 89.7 | BLASTN svg | BLASTP svg |
NC_012785:638000 | 638000 | 661466 | 23467 | Kosmotoga olearia TBF 19.5.1, complete genome | 2e-13 | 85.7 | BLASTN svg | BLASTP svg |
NC_013316:3863728* | 3863728 | 3886144 | 22417 | Clostridium difficile R20291, complete genome | 1e-11 | 79.8 | BLASTN svg | BLASTP svg |
NC_009089:3998347* | 3998347 | 4020740 | 22394 | Clostridium difficile 630, complete genome | 1e-11 | 79.8 | BLASTN svg | BLASTP svg |
NC_013406:781308 | 781308 | 809617 | 28310 | Paenibacillus sp. Y412MC10 chromosome, complete genome | 6e-10 | 73.8 | BLASTN svg | BLASTP svg |
NC_009718:1470972 | 1470972 | 1511209 | 40238 | Fervidobacterium nodosum Rt17-B1, complete genome | 3e-09 | 71.9 | BLASTN svg | BLASTP svg |
NC_003366:1427785 | 1427785 | 1450275 | 22491 | Clostridium perfringens str. 13, complete genome | 1e-08 | 69.9 | BLASTN svg | BLASTP svg |
NC_015275:3976631* | 3976631 | 3995748 | 19118 | Clostridium lentocellum DSM 5427 chromosome, complete genome | 2e-07 | 65.9 | BLASTN svg | BLASTP svg |
NC_010730:1519458* | 1519458 | 1542597 | 23140 | Sulfurihydrogenibium sp. YO3AOP1, complete genome | 2e-07 | 65.9 | BLASTN svg | BLASTP svg |
NC_019942:1211535 | 1211535 | 1241315 | 29781 | Aciduliprofundum sp. MAR08-339, complete genome | 6e-07 | 63.9 | BLASTN svg | BLASTP svg |