Pre_GI: BLASTP Hits

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Query: NC_009698:3046833:3060142 Clostridium botulinum A str. Hall chromosome, complete genome

Start: 3060142, End: 3060405, Length: 264

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: Clostridium botulinum A strain Hall was received at Fort Detrick from Harvard University in 1947. The strain is presumably one from Dr. Ivan Hall's collection, but the exact strain number has been lost. This strain produces high amounts of type A toxin. Produces botulinum, one of the most potent toxins known. This genus comprises about 150 metabolically diverse species of anaerobes that are ubiquitous in virtually all anoxic habitats where organic compounds are present, including soils, aquatic sediments and the intestinal tracts of animals and humans. This shape is attributed to the presence of endospores that develop under conditions unfavorable for vegetative growth and distend single cells terminally or sub-terminally. Spores germinate under conditions favorable for vegetative growth, such as anaerobiosis and presence of organic substrates. It is believed that present day Mollicutes (Eubacteria) have evolved regressively (i.e., by genome reduction) from gram-positive clostridia-like ancestors with a low GC content in DNA. This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin. Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_009699:3217315:323063532306353230898264Clostridium botulinum F str. Langeland chromosome, complete genomecell division topological specificity factor MinE6e-41166
NC_012563:3416509:342659434265943426857264Clostridium botulinum A2 str. Kyoto, complete genomecell division topological specificity factor MinE6e-41166
NC_010516:3234791:324811132481113248374264Clostridium botulinum B1 str. Okra, complete genomecell division topological specificity factor MinE6e-41166
NC_014328:794000:808058808058808324267Clostridium ljungdahlii ATCC 49587 chromosome, complete genomeputative septum formation topological specificity factor3e-25113
NC_021182:2160580:217632321763232176592270Clostridium pasteurianum BC1, complete genomecell division topological specificity factor MinE3e-23106
NC_015687:1377367:139678013967801397052273Clostridium acetobutylicum DSM 1731 chromosome, complete genomeCell division topological specificity factor2e-21100
NC_017295:1375180:139459313945931394865273Clostridium acetobutylicum EA 2018 chromosome, complete genomeCell division topological specificity factor MinE2e-21100
NC_009633:2350892:236514123651412365425285Alkaliphilus metalliredigens QYMF chromosome, complete genomecell division topological specificity factor MinE4e-1890.1
NC_003030:1375764:139517213951721395522351Clostridium acetobutylicum ATCC 824, complete genome1e-1685.5
NC_009617:588897:599925599925600194270Clostridium beijerinckii NCIMB 8052 chromosome, complete genomecell division topological specificity factor MinE3e-1684
NC_017179:1197763:121813712181371218421285Clostridium difficile BI1, complete genomecell division topological specificity factor MinE4e-1580.1
NC_013315:1187986:120836012083601208644285Clostridium difficile CD196 chromosome, complete genomecell division topological specificity factor MinE4e-1580.1
NC_009089:1329826:135020013502001350484285Clostridium difficile 630, complete genomecell division topological specificity factor4e-1580.1
NC_020291:5778999:579695257969525797221270Clostridium saccharoperbutylacetonicum N1-4(HMT), complete genomecell division topological specificity factor MinE2e-1478.2
NC_016584:5388500:540311854031185403396279Desulfosporosinus orientis DSM 765 chromosome, complete genomecell division topological specificity factor MinE6e-1269.7
NC_018515:4334240:436903243690324369325294Desulfosporosinus meridiei DSM 13257 chromosome, complete genomecell division topological specificity factor MinE6e-1269.3
NC_007513:1764739:178632017863201786607288Synechococcus sp. CC9902, complete genomeSeptum formation topological specificity factor MinE2e-1064.3
NC_014221:38000:477154771547954240Truepera radiovictrix DSM 17093 chromosome, complete genomecell division topological specificity factor MinE2e-0961.2
NC_015587:1232642:125561412556141255853240Hydrogenobaculum sp. SHO chromosome, complete genomecell division topological specificity factor MinE2e-0857.8
NC_011126:1241655:126493812649381265177240Hydrogenobaculum sp. Y04AAS1, complete genomecell division topological specificity factor MinE2e-0857.8
NC_020411:1232962:125593912559391256178240Hydrogenobaculum sp. HO, complete genomecell division topological specificity factor MinE2e-0857.8
NC_015557:1232772:125574412557441255983240Hydrogenobaculum sp. 3684 chromosome, complete genomeCell division topological specificity factor2e-0857.8
NC_011297:1224749:123300412330041233246243Dictyoglomus thermophilum H-6-12, complete genomecell division topological specificity factor MinE2e-0857.4
NC_011661:1411383:141326614132661413508243Dictyoglomus turgidum DSM 6724, complete genomecell division topological specificity factor MinE3e-0857
NC_016012:396910:397722397722397985264Candidatus Arthromitus sp. SFB-rat-Yit, complete genomecell division topological specificity factor MinE5e-0856.6
NC_008463:1912348:191454519145451914799255Pseudomonas aeruginosa UCBPP-PA14, complete genomecell division topological specificity factor3e-0650.4
NC_005773:1851116:186580718658071866061255Pseudomonas syringae pv. phaseolicola 1448A, complete genomecell division topological specificity factor MinE5e-0649.7