Pre_GI Gene

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Host: NC_010516 NEIGHBOURS BLASTN Download Island sequence Download Island gene sequence(s)

NC_010516:3234791 Clostridium botulinum B1 str. Okra, complete genome

Host Lineage: Clostridium botulinum; Clostridium; Clostridiaceae; Clostridiales; Firmicutes; Bacteria

General Information: This organism produces one of the most potent and deadly neurotoxins known, a botulinum toxin that prevents the release of acetylcholine at the neuromuscular junction, thereby inhibiting muscle contraction and causing paralysis. In most cases the diseased person dies of asphyxiation as a result of paralysis of chest muscles involved in breathing. The spores are heat-resistant and can survive in inadequately heated, prepared, or processed foods. Spores germinate under favorable conditions (anaerobiosis and substrate-rich environment) and bacteria start propagating very rapidly, producing the toxin.Botulinum toxin, and C. botulinum cells, has been found in a wide variety of foods, including canned ones. Almost any food that has a high pH (above 4.6) can support growth of the bacterium. Honey is the most common vehicle for infection in infants. Food poisoning through C. botulinum is the most frequent type of infection caused by this bacterium. The wound botulism that occurs when C. botulinum infects an individual via an open wound is much rarer and is very similar to tetanus disease. There are several types of botulinum toxin known (type A through type F), all of them being neurotoxic polypeptides. The most common and widely distributed are strains and serovars of C. botulinum that produce type A toxin.

This island contains ribosomal proteins or RNA related elements and may indicate a False Positive Prediction!

StartEndLengthCDS descriptionQuickGO ontologyBLASTP
323479132360651275putative cell envelope-related function transcriptional attenuatorQuickGO ontologyBLASTP
32360763236645570HDIG domain proteinQuickGO ontologyBLASTP
32367283237333606nicotinate nucleotide adenylyltransferaseQuickGO ontologyBLASTP
32375763237869294putative RNA-binding proteinQuickGO ontologyBLASTP
323789632391701275Spo0B-associated GTP-binding proteinQuickGO ontologyBLASTP
32395493239851303ribosomal protein L27QuickGO ontologyBLASTP
32398543240180327hypothetical proteinBLASTP
32401833240497315ribosomal protein L21QuickGO ontologyBLASTP
324062132420601440ribonuclease RneRng familyQuickGO ontologyBLASTP
32422293242942714hypothetical proteinBLASTP
324292032447701851radical SAM domain proteinQuickGO ontologyBLASTP
32448833245734852putative metalloproteaseQuickGO ontologyBLASTP
32457893246574786peptidase family M23M37QuickGO ontologyBLASTP
324689432480121119rod shape-determining protein RodAQuickGO ontologyBLASTP
32481113248374264cell division topological specificity factor MinEQuickGO ontologyBLASTP
32483883249185798septum site-determining protein MinDQuickGO ontologyBLASTP
32492033249832630septum site-determining protein MinCQuickGO ontologyBLASTP
325000732527812775penicillin-binding proteinQuickGO ontologyBLASTP
32528013253292492rod shape-determining protein MreDQuickGO ontologyBLASTP
32533033254148846rod shape-determining protein MreCQuickGO ontologyBLASTP
325415532551651011rod shape-determining protein MreBQuickGO ontologyBLASTP
32551943255880687DNA repair protein RadC familyQuickGO ontologyBLASTP
32558953256479585maf proteinQuickGO ontologyBLASTP
32564953256752258hypothetical proteinBLASTP
32568623257563702hypothetical proteinBLASTP
32577893258328540hypothetical proteinBLASTP