Pre_GI: BLASTP Hits

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Query: NC_009142:4046376:4063010 Saccharopolyspora erythraea NRRL 2338, complete genome

Start: 4063010, End: 4064185, Length: 1176

Host Lineage: Saccharopolyspora erythraea; Saccharopolyspora; Pseudonocardiaceae; Actinomycetales; Actinobacteria; Bacteria

General Information: Source of the antibiotic erythromycin. Saccharopolyspora erythraea is the soil bacterium that produces the industrially important antibiotic erythromycin A. Erythromycin is a clinically important and potent macrolide antibiotic. It is used to treat infections caused by several prokaryotic pathogens such as Streptococcus, Staphylococcus, Mycoplasma, Ureaplasma, Chlamydia and Legionella. Production of this antibiotic is lower than others in the same class, such as penicillin or cephalosporin, which has led to the development of a genetic system to attempt to enhance the production of erythromycin.




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SubjectStartEndLengthSubject Host DescriptionCDS descriptionE-valueBit score
NC_018750:5078705:5099429509942951010001572Streptomyces venezuelae ATCC 10712, complete genomeAlkaline serine exoprotease A precursor1e-91337
NC_013093:7722436:7726642772664277282011560Actinosynnema mirum DSM 43827, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin3e-88325
NC_019673:2635585:2644579264457926457661188Saccharothrix espanaensis DSM 44229 complete genomeExtracellular serine proteinase2e-85316
NC_017030:7514500:7515131751513175171251995Corallococcus coralloides DSM 2259 chromosome, complete genomealkaline serine exoprotease A precursor3e-83308
NC_018868:1352000:1375134137513413769781845Simiduia agarivorans SA1 = DSM 21679 chromosome, complete genomepeptidase S8/S53 subtilisin kexin sedolisin2e-77289
NC_013093:2599591:2616167261616726178581692Actinosynnema mirum DSM 43827, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin1e-75284
NC_015387:2042042:2042042204204220436041563Marinithermus hydrothermalis DSM 14884 chromosome, complete genomeAqualysin 13e-75282
NC_019673:8161242:8164613816461381664571845Saccharothrix espanaensis DSM 44229 complete genomePeptidase S8/S53, subtilisin kexin sedolisin1e-72273
NC_019673:2635585:2640082264008226413351254Saccharothrix espanaensis DSM 44229 complete genomeAqualysin-1 like protein2e-72273
NC_019673:189487:2079242079242094411518Saccharothrix espanaensis DSM 44229 complete genomeAqualysin-1 like protein6e-68258
NC_013093:2230171:2230171223017122317151545Actinosynnema mirum DSM 43827, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin8e-68257
NC_010572:8352462:8357913835791383591271215Streptomyces griseus subsp. griseus NBRC 13350, complete genomeputative secreted subtilisin-like serine protease1e-67257
NC_019673:2635585:2642597264259726437931197Saccharothrix espanaensis DSM 44229 complete genomePeptidase S8/S53, subtilisin kexin sedolisin3e-66252
NC_019673:2635585:2641410264141026425971188Saccharothrix espanaensis DSM 44229 complete genomeAqualysin-1 like protein2e-64246
NC_016109:116995:1379391379391394951557Kitasatospora setae KM-6054, complete genomeputative peptidase S08 family protein7e-63241
NC_010617:55493:6594465944671941251Kocuria rhizophila DC2201, complete genomesubtilisin family peptidase2e-60233
NC_014623:8648000:8651814865181486529921179Stigmatella aurantiaca DW4/3-1 chromosome, complete genomealkaline serine exoprotease a3e-58226
NC_014623:6095658:6100843610084361020121170Stigmatella aurantiaca DW4/3-1 chromosome, complete genomepeptidase s8 and s535e-51202
NC_009953:3224412:3227980322798032291941215Salinispora arenicola CNS-205 chromosome, complete genomepeptidase S8/S53 subtilisin kexin sedolisin2e-50200
NC_020126:8287556:8304315830431583057031389Myxococcus stipitatus DSM 14675, complete genomealkaline serine exoprotease A precursor3e-47189
NC_013510:329999:3327593327593339461188Thermomonospora curvata DSM 43183, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin2e-44180
NC_013440:1131376:1133288113328811346161329Haliangium ochraceum DSM 14365, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin1e-38160
NC_013510:1637730:1657273165727316584931221Thermomonospora curvata DSM 43183, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin3e-33142
NC_006177:520055:5285655285655302621698Symbiobacterium thermophilum IAM 14863, complete genomealkaline proteinase8e-26118
NC_012491:1838432:18526691852669186313210464Brevibacillus brevis NBRC 100599, complete genomeputative extracellular serine protease precursor2e-25117
NC_012804:348235:3482353482353502442010Thermococcus gammatolerans EJ3, complete genomeSubtilisin-like serine protease (subtilase)2e-23110
NC_015520:224136:2513782513782550163639Mahella australiensis 50-1 BON chromosome, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin8e-23108
NC_007644:2099878:2116223211622321174221200Moorella thermoacetica ATCC 39073, complete genomePeptidase S8 and S53, subtilisin, kexin, sedolisin1e-21104
NC_012491:1838432:1838432183843218461747743Brevibacillus brevis NBRC 100599, complete genomeputative extracellular serine protease precursor2e-20100
NC_006322:1415863:141862214186221419575954Bacillus licheniformis ATCC 14580, complete genomeIspA1e-1997.8
NC_006270:1415001:141776014177601418713954Bacillus licheniformis ATCC 14580, complete genomeintracellular serine protease1e-1997.8
NC_014377:480158:4846834846834858431161Thermosediminibacter oceani DSM 16646 chromosome, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin7e-1892
NC_014393:4951742:4966805496680549701283324Clostridium cellulovorans 743B chromosome, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin1e-1791.3
NC_010296:1081728:1085659108565910932637605Microcystis aeruginosa NIES-843, complete genomeputative peptidase6e-1788.6
NC_010718:2265447:2266654226665422677661113Natranaerobius thermophilus JW/NM-WN-LF, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin1e-1688.2
NC_014393:4951742:4958193495819349621043912Clostridium cellulovorans 743B chromosome, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin1e-1687.8
NC_014221:591785:5931055931055954712367Truepera radiovictrix DSM 17093 chromosome, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin1e-1687.8
NC_010718:2513917:2525222252522225285963375Natranaerobius thermophilus JW/NM-WN-LF, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin2e-1687
NC_018704:2149229:2149229214922921513852157Amphibacillus xylanus NBRC 15112, complete genomeputative S8 family peptidase2e-1584
NC_003413:1521080:1553191155319115551551965Pyrococcus furiosus DSM 3638, complete genomealkaline serine protease3e-1583.2
NC_009482:822716:8331158331158388625748Synechococcus sp. RCC307 chromosome, complete genomehypothetical protein5e-1582.4
NC_016582:1639375:1642099164209916454223324Streptomyces bingchenggensis BCW-1 chromosome, complete genomesubtilisin-like protease2e-1480.5
NC_016633:1353458:1369144136914413710571914Sphaerochaeta pleomorpha str. Grapes chromosome, complete genomesubtilisin-like serine protease2e-1480.5
NC_007645:1698803:1722076172207617237611686Hahella chejuensis KCTC 2396, complete genomeSubtilisin-like serine protease2e-1480.5
NC_013595:4796436:4818661481866148224223762Streptosporangium roseum DSM 43021, complete genomepeptidase S8/S53 subtilisin kexin sedolisin4e-1479.3
NC_014393:4951742:4962438496243849663403903Clostridium cellulovorans 743B chromosome, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin4e-1479.3
NC_009380:1663545:1673610167361016773143705Salinispora tropica CNB-440 chromosome, complete genomepeptidase S8/S53 subtilisin kexin sedolisin7e-1478.6
NC_009482:822716:8305498305498325492001Synechococcus sp. RCC307 chromosome, complete genomehypothetical protein7e-1478.6
NC_009380:1663545:1669720166972016734123693Salinispora tropica CNB-440 chromosome, complete genomepeptidase S8/S53 subtilisin kexin sedolisin1e-1377.8
NC_004193:241480:2614702614702655464077Oceanobacillus iheyensis HTE831, complete genomemicrobial serine proteinase2e-1377.4
NC_013745:177700:2086752086752128924218Haloterrigena turkmenica DSM 5511 plasmid pHTUR02, completepeptidase S8 and S53 subtilisin kexin sedolisin2e-1377
NC_014829:4392799:4394244439424443965232280Bacillus cellulosilyticus DSM 2522 chromosome, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin2e-1377
NC_006322:1119471:1122420112242011241951776Bacillus licheniformis ATCC 14580, complete genomeEpr6e-1375.5
NC_006270:1119000:1121566112156611233411776Bacillus licheniformis ATCC 14580, complete genomeextracellular serine protease6e-1375.5
NC_014152:554656:5677745677745690991326Thermincola sp. JR, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin9e-1375.1
NC_011071:1773847:1778680177868017801851506Stenotrophomonas maltophilia R551-3, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin1e-1274.7
NC_010644:718748:7196387196387207201083Elusimicrobium minutum Pei191, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin4e-1272.8
NC_015573:2063925:2080676208067620845543879Desulfotomaculum kuznetsovii DSM 6115 chromosome, complete genomeSubtilisin5e-1272.4
NC_004193:2921103:2932880293288029341871308Oceanobacillus iheyensis HTE831, complete genomeintracellular alkaline serine proteinase5e-1272.4
NC_004193:3078730:3092370309237030945772208Oceanobacillus iheyensis HTE831, complete genomeminor extracellular serine protease7e-1272
NC_015957:8845274:8874007887400788753531347Streptomyces violaceusniger Tu 4113 chromosome, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin7e-1272
NC_019673:1988853:2004629200462920058191191Saccharothrix espanaensis DSM 44229 complete genomePeptidase S8/S53, subtilisin kexin sedolisin2e-1170.9
NC_011894:6220791:623622062362206237041822Methylobacterium nodulans ORS 2060, complete genome2e-1170.5
NC_008711:3520515:3520515352051535232232709Arthrobacter aurescens TC1, complete genomeputative serine protease, subtilase family3e-1170.1
NC_013739:5705325:5730385573038557318571473Conexibacter woesei DSM 14684, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin5e-1169.3
NC_014735:199434:2214572214572269255469Halogeometricum borinquense DSM 11551 plasmid pHBOR01, completesubtilisin-like serine protease4e-1169.3
NC_019962:1142225:1155680115568011576261947Natrinema pellirubrum DSM 15624, complete genomesubtilisin-like serine protease1e-1067.8
NC_006624:1448165:1469076146907614703441269Thermococcus kodakarensis KOD1, complete genomesubtilisin-like serine protease precursor2e-1067.4
NC_014650:304441:3044413044413079203480Geobacillus sp. Y4.1MC1 chromosome, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin2e-1067.4
NC_014366:2703226:2720964272096427222831320Gamma proteobacterium HdN1, complete genomehypothetical protein2e-1067
NC_014221:266638:2889892889892915322544Truepera radiovictrix DSM 17093 chromosome, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin5e-1065.9
NC_015660:296488:2964882964882999673480Geobacillus thermoglucosidasius C56-YS93 chromosome, completeSubtilisin6e-1065.5
NC_016894:377446:3945093945093965572049Acetobacterium woodii DSM 1030 chromosome, complete genomeserine protease6e-1065.5
NC_007645:4032668:4035608403560840369271320Hahella chejuensis KCTC 2396, complete genomeSubtilisin-like serine protease1e-0964.7
NC_010085:351689:3538503538503558321983Nitrosopumilus maritimus SCM1, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin1e-0964.3
NC_013552:207345:2240172240172252731257Dehalococcoides sp. VS, complete genomesubtilisin-like serine protease precursor2e-0963.5
NC_015957:1968587:1974713197471319759961284Streptomyces violaceusniger Tu 4113 chromosome, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin2e-0963.5
NC_010003:795355:8060958060958081342040Petrotoga mobilis SJ95, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin3e-0963.2
NC_008541:3579442:3579442357944235845055064Arthrobacter sp. FB24 chromosome 1, complete sequencepeptidase S8 and S53, subtilisin, kexin, sedolisin3e-0963.2
NC_013595:891897:8918978918978951333237Streptosporangium roseum DSM 43021, complete genomeSubtilisin-like protein serine protease-like protein4e-0962.8
NC_015161:792955:8101798101798114771299Deinococcus proteolyticus MRP chromosome, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin6e-0962.4
NC_010572:1081236:1089713108971310920702358Streptomyces griseus subsp. griseus NBRC 13350, complete genomeputative subtilisin-like serine protease1e-0861.6
NC_014171:4708282:4711329471132947155524224Bacillus thuringiensis BMB171 chromosome, complete genomeminor extracellular protease VpR1e-0861.6
NC_017208:4845281:4848329484832948523934065Bacillus thuringiensis serovar chinensis CT-43 chromosome, completeminor extracellular protease VpR1e-0861.2
NC_005140:340000:3404283404283424522025Vibrio vulnificus YJ016 chromosome II, complete sequencesubtilisin-like serine protease1e-0861.2
NC_014966:328056:3280563280563300802025Vibrio vulnificus MO6-24/O chromosome II, complete sequenceregulatory P domain of the subtilisin-like proprotein convertase1e-0860.8
NC_012796:4075583:4075583407558340770911509Desulfovibrio magneticus RS-1, complete genomealkaline serine protease4e-0859.7
NC_013929:1119384:1119384111938411229533570Streptomyces scabiei 87.22 chromosome, complete genomepeptidase5e-0859.3
NC_021184:4524500:4541238454123845445853348Desulfotomaculum gibsoniae DSM 7213, complete genomesubtilisin-like serine protease7e-0858.9
NC_008700:3927896:3942818394281839443621545Shewanella amazonensis SB2B, complete genomecold-active alkaline serine protease7e-0858.9
NC_015064:3370840:3370840337084033727561917Acidobacterium sp. MP5ACTX9 chromosome, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin6e-0858.9
NC_007492:6372900:6385775638577563869561182Pseudomonas fluorescens PfO-1, complete genomePeptidase S8 and S53, subtilisin, kexin, sedolisin9e-0858.5
NC_011757:1067543:1067543106754310707013159Methylobacterium chloromethanicum CM4, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin1e-0758.2
NC_009445:838281:8508678508678520991233Bradyrhizobium sp. ORS 278 chromosome, complete genomesubtilisin-like serine protease1e-0757.8
NC_011894:3029964:3060098306009830617021605Methylobacterium nodulans ORS 2060, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin3e-0757
NC_014471:217279:2172792172792197862508Ignisphaera aggregans DSM 17230 chromosome, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin3e-0756.6
NC_007426:2248000:2256714225671422584411728Natronomonas pharaonis DSM 2160, complete genomesubtilisin-like serine protease6e-0755.8
NC_013166:417862:4262354262354277431509Kangiella koreensis DSM 16069, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin8e-0755.1
NC_015711:8169752:8198537819853781999701434Myxococcus fulvus HW-1 chromosome, complete genomepeptidase S8/S53 subtilisin kexin sedolisin1e-0654.7
NC_013947:4917711:4925253492525349265181266Stackebrandtia nassauensis DSM 44728 chromosome, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin2e-0654.3
NC_014624:2912527:2919353291935329225743222Eubacterium limosum KIST612 chromosome, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin3e-0653.5
NC_013061:4286913:4293074429307442948341761Pedobacter heparinus DSM 2366, complete genomepeptidase S8 and S53 subtilisin kexin sedolisin5e-0652.8
NC_012778:688621:705429705429706235807Eubacterium eligens ATCC 27750, complete genomehypothetical protein7e-0652